ArticleBMC public health2022
Cognitive reserve over life course and 7-year trajectories of cognitive decline: results from China health and retirement longitudinal study.
Article in BMC public health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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14 citing papers in PubMed.
- Oral Health Status, Knowledge, Hygiene Behavior and Cognitive Function Among Older Adults in Shanghai, China.Behavioral sciences (Basel, Switzerland) · 2026Article
- Cross-cultural adaptation and psychometric evaluation of the Chinese version of the short version of the Cognitive Reserve Index Questionnaire (s-CRIq): a cross-sectional study.BMC psychiatry · 2026Article
- Predicting mild cognitive impairment among rural older adults in China: development and validation of a risk prediction model.BMC geriatrics · 2026Article
- Urban-rural differences and bidirectional association between social participation and cognitive function among Chinese older adults: a 10-year prospective cohort study.Archives of public health = Archives belges de sante publique · 2025Article
- The association between cognitive reserve and cognitive function trajectories in older adults: a Chinese nationally representative cohort study with group-based trajectory modeling.BMC public health · 2025Article
- Prevalence of Cognitive Impairment and Its Associated Factors in a Rural Area of Ernakulam District, Kerala, India.Cureus · 2025Article
- Shorter Telomere Length in Individuals with Neurocognitive Disorder andInternational journal of molecular sciences · 2025Article
- Article
- Data-driven frailty and reserve phenotypes in older outpatients: a cluster analysis of complementary geriatric assessment.Frontiers in aging · 2025Article
- Article
- Longitudinal validation of cognitive reserve proxy measures: a cohort study in a rural Chinese community.Alzheimer's research & therapy · 2024Article
- Neighborhood Cohesion Across the Life Course and Effects on Cognitive Aging.The journals of gerontology. Series B, Psychological sciences and social sciences · 2023Article
- A bidirectional relationship between cognitive reserve and cognition among older adults in a rural Chinese community: a cross-lagged design.Frontiers in psychology · 2023Article
- Association of Lifelong Cognitive Reserve with Dementia and Mild Cognitive Impairment among Older Adults with Limited Formal Education: A Population-Based Cohort Study.Dementia and geriatric cognitive disorders · 2023Article
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Abstract
backgroundCognitive reserve (CR) could partly explain the individual heterogeneity in cognitive decline. No study measured CR from a life course perspective and investigated the association between CR and trajectories of cognitive decline in older Chinese adults.
methodsData of 6795 Chinese adults aged 60+ from China Health and Retirement Longitudinal Study were used. Global cognition score (0-32) was assessed in all four waves. A life-course CR score was constructed using markers of childhood circumstance, education, highest occupational class, and leisure activities in later life. Latent growth curve modelling (LGCM) was applied to assess the association between CR and trajectories of cognitive decline.
resultsFor the life-course CR, factor loadings of markers in adulthood and later life were larger than that of markers in childhood. The life-course CR score (ranged between - 2.727 and 6.537, SD: 1.74) was higher in urban Chinese adults (0.75, SD: 1.90) than in rural Chinese adults (- 0.50, SD: 1.43). The unconditional LGCM results showed that urban older Chinese adults had better global cognition at baseline (intercept: 15.010, 95% CI: 14.783, 15.237) and a slower rate of cognitive decline per year (linear slope: -0.394, 95% CI: - 0.508, - 0.281) than their rural counterparts (intercept: 12.144, 95% CI: 11.960, 12.329; linear slope: -0.498, 95% CI: - 0.588, - 0.408). After controlling for all covariates, one-unit higher CR score was associated with 1.615 (95% CI: 1.521, 1.709) and 1.768 (95% CI: 1.659, 1.876) unit higher global cognition at baseline for urban and rural older Chinese adults, respectively. The slower rate of cognitive decline associated with higher CR was more evident in rural residents (slope: 0.083, 95% CI: 0.057, 0.108) than in their urban counterparts (0.054, 95% CI: 0.031, 0.077).
conclusionsCR was associated with better baseline cognition and slower cognitive decline in Chinese older adults. Although rural residents were disadvantaged in both CR and cognition, the protective effect of CR against cognitive decline was stronger for them than in those who live in urban area.
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