Observational studyPloS one2022
Merged swing-muscle synergies and their relation to walking characteristics in subacute post-stroke patients: An observational study.
Observational study in PloS one, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 21 citations in OpenAlex.
- Relationship between lower limb muscle coordination and knee flexion angle during the swing phase of gait in post-stroke individuals.Journal of neuroengineering and rehabilitation · 2026Article
- Muscle synergy-driven ensemble learning framework for individualized stroke gait rehabilitation.Scientific reports · 2025Article
- Generalizability of neuromuscular coordination in the human upper extremity after stroke and its implications in neurorehabilitation.Journal of neuroengineering and rehabilitation · 2025Article
- Post-stroke Stiff-Knee gait: are there different types or different severity levels?Journal of neuroengineering and rehabilitation · 2025Article
- Comparative analysis of muscle synergies in gait of stroke patients and healthy controls.Frontiers in human neuroscience · 2025Article
- Quantitative evaluation method of stroke association based on multidimensional gait parameters by using machine learning.Frontiers in neuroinformatics · 2025Article
- Characterization of muscle synergy similarity and adaptation in hip exoskeleton-assisted locomotion.Frontiers in bioengineering and biotechnology · 2025Article
- Application of Muscle Synergies for Gait Rehabilitation After Stroke: Implications for Future Research.Neurology international · 2024Review
- Altered muscle synergy structure in patients with poststroke stiff knee gait.Scientific reports · 2024Article
- Increased trial-to-trial similarity and reduced temporal overlap of muscle synergy activation coefficients manifest during learning and with increasing movement proficiency.Scientific reports · 2024Article
- Characteristics of limb kinematics in the gait disorders of post-stroke patients.Scientific reports · 2024Article
- Association Between Temporal Asymmetry and Muscle Synergy During Walking With Rhythmic Auditory Cueing in Survivors of Stroke Living With Impairments.Archives of rehabilitation research and clinical translation · 2022Article
Corrections and comments
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Authors and funding
10 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In post-stroke patients, muscle synergy (the coordination of motor modules during walking) is impaired. In some patients, the muscle synergy termed module 1 (hip/knee extensors) is merged with module 2 (ankle plantar flexors), and in other cases, module 1 is merged with module 4 (knee flexors). However, post-stroke individuals with a merging pattern of module 3 (hip flexor and ankle dorsiflexor) and module 4, which is the swing-muscle synergy, have not been reported. This study aimed to determine the muscle-synergy merging subtypes of post-stroke during comfortable walking speed (cws). We also examined the effect of experimental lower-limb angle modulation on the muscle synergy patterns of walking in each subtype. Forty-one participants were assessed under three conditions: cws, long stepping on the paretic side (p-long), and long stepping on the non-paretic side (np-long). Lower-limb flexion and extension angles and the electromyogram were measured during walking. Subtype classification was based on the merging pattern of the muscle synergies, and we examined the effect of different lower-limb angles on the muscle synergies. We identified three merging subtypes: module 1 with module 2 (subtype 1), module 1 with module 4 (subtype 2), and module 3 with module 4 (subtype 3). In the cws condition, the lower-limb flexion angle was reduced in subtype 3, and the lower-limb extension angle was decreased in subtype 1. A more complex muscle synergy was observed only in subtype 3 in the p-long condition versus cws (p = 0.036). This subtype classification of walking impairments based on the merging pattern of the muscle synergies could be useful for the selection of a rehabilitation strategy according to the individual's particular neurological condition. Rehabilitation with increased lower-limb flexion may be effective for the training of patients with merging of modules 3 and 4 in comfortable walking.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.