ArticleScience advances2022
The costs and benefits of primary prevention of zoonotic pandemics.
Article in Science advances, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 115 papers, 5 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
115 citing papers in PubMed, 5 syntheses or guidelines pooled it.
- Systematic Review and Meta-Analysis of Emerging Viral Zoonotic Diseases, 2016-2026.Transboundary and emerging diseases · 2026Pooled it
- Zoonotic pathogens in equids in Central Europe: a systematic review.BMC veterinary research · 2025Pooled it
- Community Engagement Within the Evaluation of Public Policies for Zoonotic Spillover Prevention: A Secondary Matrix Analysis.International journal of environmental research and public health · 2025Pooled it
- The Effect of Temperature on the Distribution of Zoonotic Pathogens in Livestock and Wildlife Populations: A Systematic Review.Transboundary and emerging diseases · 2023Pooled it
- The dual burden of animal and human zoonoses: A systematic review.PLoS neglected tropical diseases · 2022Pooled it
- Exploring the impacts of wildlife trade on zoonotic spillover and disease outbreaks: A multiple-perspective study.One health (Amsterdam, Netherlands) · 2026Article
- Priorities and opportunities for strengthening hygiene and One Health alignment in research, policy and practice.BMC global and public health · 2026Review
- Wildlife Trade and Genetic Basis of Disease Susceptibility: A Review.International journal of immunogenetics · 2026Review
- A multiregional serosurvey of RNA virus-reactive antibodies in bats and rodents reveals the enzootic presence of flavi- and paramyxoviruses in African Pteropodidae.PLoS neglected tropical diseases · 2026Article
- Article
- Qualitative Assessment of One Health Operationalization at the Central Level and in Two Border Districts of Sierra Leone.Public health challenges · 2026Article
- Climate Change Impacts on One Health Systems: A Narrative Review of Empirical Evidence and Policy Responses.Public health challenges · 2026Review
- The Role of Insurance Mechanisms in Managing Zoonotic Risk Within the One Health Approach.Healthcare (Basel, Switzerland) · 2026Review
- Article
- Human-animal contact and zoonotic exposure from wild and domestic animals: A cross-sectional study in wildlife-rich areas of Bolivia, Chile, and Guatemala.One health (Amsterdam, Netherlands) · 2026Article
- Regional Lassa virus lineages select for divergent MHC-I repertoires in Mastomys natalensis rodents.PLoS pathogens · 2026Article
- Cost effectiveness of the Texas wildlife rabies Border Maintenance Zone.PLoS neglected tropical diseases · 2026Article
- Overcoming Barriers to One Health Surveillance Implementation.Health security · 2026Article
- A stochastic programming approach for dynamic allocation of bed capacity and assignment of patients to collaborating hospitals during pandemic outbreaks.Health care management science · 2026Article
- Article
55 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
20 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The lives lost and economic costs of viral zoonotic pandemics have steadily increased over the past century. Prominent policymakers have promoted plans that argue the best ways to address future pandemic catastrophes should entail, "detecting and containing emerging zoonotic threats." In other words, we should take actions only after humans get sick. We sharply disagree. Humans have extensive contact with wildlife known to harbor vast numbers of viruses, many of which have not yet spilled into humans. We compute the annualized damages from emerging viral zoonoses. We explore three practical actions to minimize the impact of future pandemics: better surveillance of pathogen spillover and development of global databases of virus genomics and serology, better management of wildlife trade, and substantial reduction of deforestation. We find that these primary pandemic prevention actions cost less than 1/20th the value of lives lost each year to emerging viral zoonoses and have substantial cobenefits.
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.