ArticleMedical & biological engineering & computing2022
Study of the significance of parameters and their interaction on assessing femoral fracture risk by quantitative statistical analysis.
Article in Medical & biological engineering & computing, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Risk analysis for subsequent fracture of osteoporotic fractures in Chinese women over age 60: a nationwide cross-sectional study.Scientific reports · 2024Article
- SSDL-an automated semi-supervised deep learning approach for patient-specific 3D reconstruction of proximal femur from QCT images.Medical & biological engineering & computing · 2024Article
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Authors and funding
4 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Early assessment of hip fracture helps develop therapeutic and preventive mechanisms that may reduce the occurrence of hip fracture. An accurate assessment of hip fracture risk requires proper consideration of the loads, the physiological and morphological parameters, and the interactions between these parameters. Hence, this study aims at analyzing the significance of parameters and their interactions by conducting a quantitative statistical analysis. A multiple regression model was developed considering different loading directions during a sideways fall (angle [Formula: see text] and [Formula: see text] on the coronal and transverse planes, respectively), age, gender, patient weight, height, and femur morphology as independent parameters and Fracture Risk Index (FRI) as a dependent parameter. Strain-based criteria were used for the calculation of FRI with the maximum principal strain obtained from quantitative computed tomography-based finite element analysis. The statistical result shows that [Formula: see text] [Formula: see text], age [Formula: see text], true moment length [Formula: see text], gender [Formula: see text], FNA [Formula: see text], height [Formula: see text], and FSL [Formula: see text] significantly affect FRI where [Formula: see text] is the most influential parameter. The significance of two-level interaction [Formula: see text] and three-level interaction [Formula: see text] shows that the effect of parameters is dissimilar and depends on other parameters suggesting the variability of FRI from person to person.
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