Evidence map›Paper›PMID 35119338›Full record

ArticleJournal of medical screening2022

Recovery of the breast screening programme following pandemic-related delays: Should we focus on round length or uptake?

Stephen W Duffy, Sue Hudson, Daniel Vulkan, Thomas E Duffy, Kathie Binysh

Abstract read
In one paragraph

Article in Journal of medical screening, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Trial
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Stephen W Duffy105714Wolfson Institute of Population Health, Queen Mary University of London, London, UK.
Sue HudsonPeel & Schriek Consulting Limited, London, UK.ORCID 0000-0003-2175-4939
Daniel Vulkan105714Wolfson Institute of Population Health, Queen Mary University of London, London, UK.ORCID 0000-0003-4738-9378
Thomas E DuffyResearch Department of Behavioural Science and Health, 4919University College London, London, UK.ORCID 0000-0002-3565-6590
Kathie BinyshHead of Screening, 53249NHS England & Improvement (London), London, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe NHS Breast Screening programme is recovering from the hiatus in screening in 2020 due to the COVID-19 pandemic. Currently, open rather than timed invitations are issued, which leads to lower uptake but more rapid coverage of the eligible population by invitation and therefore closer adherence to a round length of 3 years. We aimed to estimate the likely effect on numbers of cancers detected at incident screens of a range of round lengths and uptake rates.

methodsWe assumed exponential distributions of time to incidence of preclinical screen-detectable cancer and of time to progression thereafter to symptomatic clinical disease. We derived numerical values of these, along with screening sensitivity, from published research results and statistics from the NHS Breast Screening programme. These were used to calculate numbers of cancers detected at incident screens at ages 51-70 by round length and uptake rates.

resultsWe found that in a homogeneous population of cancers, a 4-year round length with uptake of 62%, as observed with timed appointments in London before the pandemic, would result in 295 cancers screen detected per 10,000 invited, compared to 222 cancers with a 3-year round and uptake of 46%, as observed in London during the recovery period. Similar results were found when we posited two populations, one of rapidly progressing and one of slowly progressing cancers.

conclusionsIt may be more productive in terms of early detection to focus on uptake rather than round length in the programme's recovery from the pandemic.

Indexed as

Breast NeoplasmsCOVID-19AgedAppointments and SchedulesEarly Detection of CancerFemaleHumansIncidenceMammographyMass ScreeningMiddle AgedPandemicsbreast screeninground lengthuptake

Identifiers

PMID35119338
PMCPMC9087308

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.