Evidence map›Paper›PMID 35119295›Full record

ArticleBone & joint open2022

Dual modality of vertebral body tethering : anterior scoliosis correction versus growth modulation with mean follow-up of five years.

Jason Bernard, Timothy Bishop, Jan Herzog, Shahnawaz Haleem, Cristina Lupu, Bisola Ajayi, Darren F Lui

Open access · greenAbstract read
In one paragraph

Article in Bone & joint open, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. The Effects of Vertebral Body Tethering on the Intervertebral Discs and Facet Joints: A Numerical Analysis.International journal for numerical methods in biomedical engineering · 2025
    Article
  9. Review
  10. Article
  11. An investigation of range of motion preservation in fusionless anterior double screw and cord constructs for scoliosis correction.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2023
    Article
  12. Article
  13. Article
  14. The timing of tether breakage influences clinical results after VBT.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2022
    Article
  15. Article
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Jason BernardComplex Spinal Division, Neurosciences Atkinson Morley Wing, St. George's Hospital, London, UK.
Timothy BishopComplex Spinal Division, Neurosciences Atkinson Morley Wing, St. George's Hospital, London, UK.
Jan HerzogComplex Spinal Division, Neurosciences Atkinson Morley Wing, St. George's Hospital, London, UK.
Shahnawaz HaleemComplex Spinal Division, Neurosciences Atkinson Morley Wing, St. George's Hospital, London, UK.
Cristina LupuComplex Spinal Division, Neurosciences Atkinson Morley Wing, St. George's Hospital, London, UK.
Bisola AjayiComplex Spinal Division, Neurosciences Atkinson Morley Wing, St. George's Hospital, London, UK.
Darren F LuiComplex Spinal Division, Neurosciences Atkinson Morley Wing, St. George's Hospital, London, UK.ORCID 0000-0003-2121-6786
Atkins (United Kingdom) · GBSt George's Hospital · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsVertebral body tethering (VBT) is a non-fusion technique to correct scoliosis. It allows correction of scoliosis through growth modulation (GM) by tethering the convex side to allow concave unrestricted growth similar to the hemiepiphysiodesis concept. The other modality is anterior scoliosis correction (ASC) where the tether is able to perform most of the correction immediately where limited growth is expected.

methodsWe conducted a retrospective analysis of clinical and radiological data of 20 patients aged between 9 and 17 years old, (with a 19 female: 1 male ratio) between January 2014 to December 2016 with a mean five-year follow-up (4 to 7).

resultsThere were ten patients in each group with a total of 23 curves operated on. VBT-GM mean age was 12.5 years (9 to 14) with a mean Risser classification of 0.63 (0 to 2) and VBT-ASC was 14.9 years (13 to 17) with a mean Risser classification of 3.66 (3 to 5). Mean preoperative VBT-GM Cobb was 47.4° (40° to 58°) with a Fulcrum unbend of 17.4 (1° to 41°), compared to VBT-ASC 56.5° (40° to 79°) with 30.6 (2° to 69°)unbend. Postoperative VBT-GM was 20.3° and VBT-ASC Cobb angle was 11.2°. The early postoperative correction rate was 54.3% versus 81% whereas Fulcrum Bending Correction Index (FBCI) was 93.1% vs 146.6%. The last Cobb angle on radiograph at mean five years' follow-up was 19.4° (VBT-GM) and 16.5° (VBT-ASC). Patients with open triradiate cartilage (TRC) had three over-corrections. Overall, 5% of patients required fusion. This one patient alone had a over-correction, a second-stage tether release, and final conversion to fusion.

conclusionWe show a high success rate (95%) in helping children avoid fusion at five years post-surgery. VBT is a safe technique for correction of scoliosis in the skeletally immature patient. This is the first report at five years that shows two methods of VBT can be employed depending on the skeletal maturity of the patient: GM and ASC. Cite this article:

Indexed as

Adolescent idiopathic scoliosisAnterior spinal correctioncartilagesCobb anglesGrowth modulationhemiepiphysiodesisRadiographsrandomized control trialretrospective analysisRisserscoliosisSkeletal maturitysurrogate markerTri-radiate cartilagetriradiate cartilage (TRC)vertebral bodyVetebral body tethering

Identifiers

PMID35119295
PMCPMC8886322
OpenAlexW4210533582

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.