Evidence map›Paper›PMID 35119218›Full record

ArticleAdvanced biology2022

CX3CR1-Expressing Myeloid Cells Regulate Host-Helminth Interaction and Lung Inflammation.

Sang Yong Kim, Mark A Barnes, Suhas Sureshchandra, Andrea R Menicucci, Jay J Patel, Ilhem Messaoudi, Meera G Nair

Open access · greenAbstract read
In one paragraph

Article in Advanced biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Sang Yong KimDivision of Biomedical Sciences, School of Medicine, University of California Riverside, Riverside, CA, 92521, USA.
Mark A BarnesDivision of Biomedical Sciences, School of Medicine, University of California Riverside, Riverside, CA, 92521, USA.
Suhas SureshchandraDepartment of Molecular Biology and Biochemistry, School of Biological Sciences, University of California, Irvine, CA, 92697-3900, USA.ORCID 0000-0002-4141-8564
Andrea R MenicucciDepartment of Molecular Biology and Biochemistry, School of Biological Sciences, University of California, Irvine, CA, 92697-3900, USA.
Jay J PatelDivision of Biomedical Sciences, School of Medicine, University of California Riverside, Riverside, CA, 92521, USA.
Ilhem MessaoudiDepartment of Molecular Biology and Biochemistry, School of Biological Sciences, University of California, Irvine, CA, 92697-3900, USA.ORCID 0000-0003-3203-2405
Meera G NairDivision of Biomedical Sciences, School of Medicine, University of California Riverside, Riverside, CA, 92521, USA.ORCID 0000-0002-1807-5161
University of California, Riverside · USUniversity of California, Irvine · US

Funding

RELMalpha-expressing macrophages mediate host disease tolerance in mucosal infectionR01AI153195 · NIAID · UNIVERSITY OF CALIFORNIA RIVERSIDE · PI NAIR, MEERA GOH · 2020 to 2024
$3.5M
RELM-alpha regulation of hookworm-induced lung inflammationR01AI091759 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI NAIR, MEERA GOH · 2011 to 2015
$2.0M
NIAID NIH HHS R01 AI091759NIAID NIH HHS R01 AI153195
6 · The paper itself

Abstract

Many helminth life cycles, including hookworm, involve a mandatory lung phase, where myeloid and granulocyte subsets interact with the helminth and respond to infection-induced lung injury. To evaluate these innate subsets in Nippostrongylus brasiliensis infection, reporter mice for myeloid cells (CX3CR1

Indexed as

MonocytesPneumoniaAnimalsCD11c AntigenCX3C Chemokine Receptor 1MiceMice, Inbred C57BLMyeloid CellsNippostrongylusCD11c AntigenCX3C Chemokine Receptor 1Cx3cr1 protein, mousechemokine receptorhelminthinnate immunitymonocyte

Identifiers

PMID35119218
PMCPMC8934291
OpenAlexW4210679500

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.