Evidence map›Paper›PMID 35118962›Full record

ArticleTurkish journal of urology2021

MRI apparent diffusion coefficient (ADC): A biomarker for prostate cancer after radiation therapy.

Michele Scialpi, Eugenio Martorana, Pietro Scialpi, Alfredo D'Andrea, Francesco Maria Mancioli, Marcello Mignogna, Aldo Di Blasi, Fabio Trippa

Abstract read
In one paragraph

Article in Turkish journal of urology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. DoesEuropean journal of nuclear medicine and molecular imaging · 2026
    Article
  2. Article
  3. IntegratedEJNMMI research · 2026
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Michele ScialpiDivision of Diagnostic Imaging, Department of Medicine and Surgery, University of Perugia, Santa Maria della Misericordia Hospital, Perugia, Italy.
Eugenio MartoranaDivision of Urology, Nuovo Ospedale Civile Sassuolo, Modena, Italy.
Pietro ScialpiDivision of Urology, Portogruaro Hospital, Venice, Italy.
Alfredo D'AndreaDivision of Radiology, ASL, Caserta, Italy.
Francesco Maria MancioliRadiation Division of Radiology, Ospedale Santa Maria, Terni, Italy.
Marcello MignognaDepartment of Oncology, Oncology Unit, S. Luca Hospital, Lucca, Italy.
Aldo Di BlasiDivision of Radiology, Tivoli Hospital, Tivoli, Italy.
Fabio TrippaDepartment of Radiotherapy, Ospedale Santa Maria, Terni, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Prostate specific antigen (PSA) remains the most used test to assess the response after therapies including the radiation therapy (RT). Apparent diffusion coefficient (ADC) derived from the conventional diffusionweighted imaging (DWI), as a part of noncontrast or biparametric MRI (bpMRI) (T2-weighted and DWI), offers diagnostic accuracy and cancer detection rate equivalent to that of multiparametric MRI. Cellular changes induced by RT can be quali-qualitatively demonstrated as early as 3months after RT as an increase in the signal intensity of the tumor on the ADC map. ADC, in association with PSA, represents a potential biomarker imaging for evaluating treatment efficacy in PCa both during and shortly after RT.

Identifiers

PMID35118962
PMCPMC9612745

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.