Evidence map›Paper›PMID 35118611›Full record

ArticleJournal of racial and ethnic health disparities2022

Cardiologists' Perspectives on BiDil and the Use of Race in Drug Prescribing.

Shawneequa L Callier, Perry W Payne, Deborah Akinniyi, Kaitlyn McPartland, Terry L Richardson, Mark A Rothstein, Charmaine D M Royal

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Article in Journal of racial and ethnic health disparities, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.2field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 1 country.

Shawneequa L CallierDepartment of Clinical Research and Leadership, School of Medicine and Health Sciences, George Washington University, Washington, DC, USA.
Perry W PayneDepartment of Clinical Research and Leadership, School of Medicine and Health Sciences, George Washington University, Washington, DC, USA. ppayne@gwu.edu.
Deborah AkinniyiSchool of Medicine, Yale University, New Haven, CT, USA.
Kaitlyn McPartlandDuke University, Durham, NC, USA.
Terry L RichardsonGeorge Washington University, Washington, DC, USA.
Mark A RothsteinInstitute for Bioethics, Health Policy and Law, School of Medicine, University of Louisville, Louisville, KY, USA.
Charmaine D M RoyalDepartment of African & African American Studies and Center on Genomics, Race, Identity, Difference, Duke University, NC, Durham, USA.
Duke University · USGeorge Washington University · USNational Human Genome Research Institute · USUniversity of Louisville · USYale University · US

Funding

Center on Genomics/Social Identity in African DiasporaP20HG003373 · NHGRI · HOWARD UNIVERSITY · PI ROYAL, CHARMAINE DAWN MARIE · 2004 to 2006
$672k
NHGRI NIH HHS P20HG03373
6 · The paper itself

Abstract

objectivesWe explored cardiologists' attitudes and prescribing patterns specific to the use of generic isosorbide dinitrate and hydralazine hydrochloride, and the fixed-dose patented drug, BiDil.

backgroundSince the Food and Drug Administration approved BiDil in 2005 with an indication for self-identified black patients, disagreement about the appropriateness of race-based drugs has intensified and led to calls for providers and researchers to abandon race-based delimitations. This paper reports empirical evidence of cardiologists' views on BiDil's race-based indication and their ongoing inertia with respect to the debate about BiDil.

methodsWe conducted a 2010 cross-sectional online survey of members of the Association of Black Cardiologists.

resultsFifty-nine cardiologists responded to the survey. Most participants (62.7%) prescribed BiDil to their patients. More than 40% of respondents did not prescribe BiDil to any non-African Americans. When considering whether to prescribe BiDil, a patient's race determined by physician assessment was the third most important factor considered by participants. The majority of participants (72.7%) selected symptoms as the most important factor. Most participants (59.2%) perceived race as defining biologically distinct individuals. Respondents prescribed BiDil more often to African American patients than non-African American patients. However, they prescribed the generic components that makeup BiDil to African Americans and non-African American patients similarly.

conclusionsThe survey provides useful findings that, when viewed within the context of ongoing debates about race-based medicine, show little progress toward appropriately utilizing BiDil to maximize health outcomes, yet, might inform the development of practical and effective guidelines concerning the use of race in medicine.

Indexed as

CardiologistsHeart FailureCross-Sectional StudiesDrug CombinationsDrug PrescriptionsHumansHydralazineIsosorbide DinitrateDrug CombinationsHydralazineIsosorbide Dinitrateisosorbide-hydralazine combinationAfrican AmericanBiDilCardiologistPrescriptionRace

Identifiers

PMID35118611
OpenAlexW4210722030

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.