Evidence map›Paper›PMID 35118575›Full record

ArticleJournal of autism and developmental disorders2023

Effect of Children's Autism Spectrum Disorder Severity on Family Strain and Sleep Quality: A Cross-Sectional Online Survey in the U.S.

Gonzalo Durán-Pacheco, Mariabeth Silkey, Michelle Johnson, Chuang Liu, Susanne Clinch, Kiely Law, Georg Loss

Open access · hybridAbstract read
In one paragraph

Article in Journal of autism and developmental disorders, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
2.1field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Short Report: An Examination of Children's Autism Traits and Their Association With Family Experience.Autism research : official journal of the International Society for Autism Research · 2026
    Article
  3. Article
  4. Article
  5. Our Challenges, Our Solutions: The Impact of Autism on Families.Journal of autism and developmental disorders · 2025
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 3 countries.

Gonzalo Durán-PachecoF. Hoffmann-La Roche Ltd., Basel, Switzerland.
Mariabeth SilkeyF. Hoffmann-La Roche Ltd., Basel, Switzerland.ORCID http://orcid.org/0000-0002-0305-7585
Michelle JohnsonRoche Products Ltd., Hexagon Place, 6 Falcon Way, Shire Park, Welwyn Garden City, AL7 1TW, UK. michelle.johnson.mj2@roche.com.ORCID http://orcid.org/0000-0001-7994-2380
Chuang LiuF. Hoffmann-La Roche Ltd., Basel, Switzerland.
Susanne ClinchRoche Products Ltd., Hexagon Place, 6 Falcon Way, Shire Park, Welwyn Garden City, AL7 1TW, UK.
Kiely LawKennedy Krieger Institute, Baltimore, MD, USA.ORCID http://orcid.org/0000-0003-2188-6106
Georg LossF. Hoffmann-La Roche Ltd., Basel, Switzerland.ORCID http://orcid.org/0000-0003-1090-812X
Roche (Switzerland) · CHRoche (United Kingdom) · GBKennedy Krieger Institute · US

Funding

Sleep and Circadian Dysfunction, Brain and Neurobehavioral Development in AutismP50HD103538 · NICHD · HUGO W. MOSER RES INST KENNEDY KRIEGER · PI S. Ali Fatemi, Bradley L Schlaggar · 2020 to 2026
$9.9M
NICHD NIH HHS P50 HD103538
6 · The paper itself

Abstract

To better understand the impact of children's autism spectrum disorder (ASD) severity on families, we evaluated pathways through which ASD severity affected child sleep quality, caregiver strain, and caregiver sleep quality. In a cross-sectional analysis through the U.S.-wide Simons Foundation Powering Autism Research for Knowledge (SPARK) cohort. Participants were caregivers of dependents with ASD aged 3-17 years (N = 3150). We found that increased severity strongly affects caregiver strain and child sleep quality. Child sleep quality was a minor mediator of increasing caregiver strain. Caregiver sleep quality depended on ASD severity only through child sleep quality and caregiver strain. Interventions aimed at improving child sleep quality or reducing caregiver strain could positively impact families of children with ASD.

Indexed as

Autism Spectrum DisorderAutistic DisorderSleep Wake DisordersCaregiversChildCross-Sectional StudiesHumansSleep QualityAutism Impact MeasureAutism spectrum disorderCaregiver strainChild healthSeveritySleep quality

Identifiers

PMID35118575
PMCPMC10123033
OpenAlexW4210448446

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.