Evidence map›Paper›PMID 35118418›Full record

ArticleReproduction & fertility2022

Q fever and early pregnancy failure: a Scottish case-control study.

Nick Wheelhouse, Sadie Kemp, Jo E B Halliday, Efstathios Alexandros Tingas, W Colin Duncan, Andrew W Horne

Open access · diamondAbstract read
In one paragraph

Article in Reproduction & fertility, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Review
  2. Evidence ofNew microbes and new infections · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Nick WheelhouseSchool of Applied Sciences, Edinburgh Napier University, Sighthill Court, Edinburgh, UK.
Sadie KempSchool of Applied Sciences, Edinburgh Napier University, Sighthill Court, Edinburgh, UK.
Jo E B HallidayInstitute of Biodiversity, Animal Health and Comparative Medicine, College of Medical Veterinary and Life Sciences, University of Glasgow, Glasgow, UK.
Efstathios Alexandros TingasSchool of Engineering & the Built Environment, Edinburgh Napier University, Merchiston Campus, Edinburgh, UK.
W Colin DuncanMRC Centre for Reproductive Health, Queen's Medical Research Institute, The University of Edinburgh, Edinburgh Bioquarter, Edinburgh, UK.ORCID 0000-0002-7170-5740
Andrew W HorneMRC Centre for Reproductive Health, Queen's Medical Research Institute, The University of Edinburgh, Edinburgh Bioquarter, Edinburgh, UK.
Edinburgh Napier University · GBMRC Centre for Reproductive Health · GBUniversity of Glasgow · GB

Funding

Medical Research Council MR/N022556/1
6 · The paper itself

Abstract

Q fever is a bacterial disease that passes between animals and humans and causes disease in both. The disease has been associated with pregnancy complications including miscarriage. This study was undertaken to identify if Q fever exposure was correlated with miscarriage in 369 women attending a pregnancy support unit in Edinburgh. The women in the study were in two groups, the miscarriage group with 251 women who had experienced a miscarriage and a control group of 118 women who had not experienced miscarriage. Three women were found to be positive for Q fever antibodies, suggesting that they had previously been exposed to the infection and all of them were from the group who had experienced miscarriage. The study indicates that Q fever is relatively rare in women attending an urban Scottish hospital suggesting that the infection is not a major cause of miscarriage in this population. However, as Q fever antibodies could only be found in women within the miscarriage group, it suggests that the infection cannot be ruled out as a potential cause of miscarriage in individual cases.

Indexed as

Abortion, SpontaneousPregnancy Complications, InfectiousQ FeverAnimalsAntibodies, BacterialCase-Control StudiesFemaleHumansPregnancyScotlandAntibodies, Bacterial

Identifiers

PMID35118418
PMCPMC8789011
OpenAlexW4200350466

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.