Evidence map›Paper›PMID 35118390›Full record

ArticleReproduction & fertility2021

Glycerophospholipids protect stallion spermatozoa from oxidative damage

Ashlee J Medica, Robert J Aitken, Garth L Nicolson, Alecia R Sheridan, Aleona Swegen, Geoffry N De Iuliis, Zamira Gibb

Open access · diamondAbstract read
In one paragraph

Article in Reproduction & fertility, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 19 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Effects of ThreeThe journal of poultry science · 2026
    Article
  5. Article
  6. Article
  7. Article
  8. Catalase in Unexpected Places: Revisiting HAntioxidants (Basel, Switzerland) · 2025
    Article
  9. In Vitro Anti-Glioblastoma Activity ofLife (Basel, Switzerland) · 2025
    Article
  10. Article
  11. Evaluation of Oxidative Stress in Mammalian Spermatozoa.Methods in molecular biology (Clifton, N.J.) · 2025
    Article
  12. Article
  13. Roles of Y-27632 on sheep sperm metabolism.Journal of animal science · 2024
    Article
  14. Article
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Ashlee J MedicaPriority Research Centre for Reproductive Science, College of Engineering, Science and Environmental, and Faculty of Health and Medicine, University of Newcastle, Callaghan, New South Wales, Australia.ORCID 0000-0001-7270-9316
Robert J AitkenPriority Research Centre for Reproductive Science, College of Engineering, Science and Environmental, and Faculty of Health and Medicine, University of Newcastle, Callaghan, New South Wales, Australia.ORCID 0000-0002-9152-156X
Garth L NicolsonInstitute for Molecular Medicine, Huntington Beach, California, USA.
Alecia R SheridanPriority Research Centre for Reproductive Science, College of Engineering, Science and Environmental, and Faculty of Health and Medicine, University of Newcastle, Callaghan, New South Wales, Australia.
Aleona SwegenPriority Research Centre for Reproductive Science, College of Engineering, Science and Environmental, and Faculty of Health and Medicine, University of Newcastle, Callaghan, New South Wales, Australia.
Geoffry N De IuliisPriority Research Centre for Reproductive Science, College of Engineering, Science and Environmental, and Faculty of Health and Medicine, University of Newcastle, Callaghan, New South Wales, Australia.
Zamira GibbPriority Research Centre for Reproductive Science, College of Engineering, Science and Environmental, and Faculty of Health and Medicine, University of Newcastle, Callaghan, New South Wales, Australia.
University of Newcastle Australia · AUInstitute for Molecular Medicine · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Stallion sperm membranes comprise a high proportion of polyunsaturated fatty acids, making stallion spermatozoa especially vulnerable to peroxidative damage from reactive oxygen species generated as a by-product of cell metabolism. Membrane lipid replacement therapy with glycerophospholipid (GPL) mixtures has been shown to reduce oxidative damage LAY SUMMARY: Sperm collection and storage is an important step in many artificial insemination and

Indexed as

GlycerophospholipidsSperm MotilityAnimalsFemaleHorsesHumansMaleOxidative StressSemenSpermatozoaGlycerophospholipidsmembrane lipid replacementreactive oxygen speciessperm membranestallion spermatozoa

Identifiers

PMID35118390
PMCPMC8801026
OpenAlexW3184133653

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.