Evidence map›Paper›PMID 35118353›Full record

ArticleiScience2022

Correlation between circulating innate lymphoid cell precursors and thymic function.

Sandra Bajana, Aneta Pankow, Kaili Liu, Martyna Michniowska, Joseph F Urban, Wei R Chen, Xiao-Hong Sun

Open access · goldAbstract read
In one paragraph

Article in iScience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.3field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Frontiers in immunology · 2025
    Article
  6. Article
  7. Review
  8. Article
  9. ILC Differentiation in the Thymus.Advances in experimental medicine and biology · 2022
    Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Sandra BajanaOklahoma Medical Research Foundation, Program in Arthritis and Clinical Immunology, 825 NE 13Street, Oklahoma City, OK 73104, USA.
Aneta PankowOklahoma Medical Research Foundation, Program in Arthritis and Clinical Immunology, 825 NE 13Street, Oklahoma City, OK 73104, USA.
Kaili LiuStephenson School of Biomedical Engineering, University of Oklahoma, Norman, OK 73104, USA.
Martyna MichniowskaOklahoma Medical Research Foundation, Program in Arthritis and Clinical Immunology, 825 NE 13Street, Oklahoma City, OK 73104, USA.
Joseph F UrbanUnited States Department of Agriculture, Agricultural Research Service, Beltsville Human Nutrition Research Center, Diet, Genomics, and Immunology Laboratory, Beltsville, MD 73104, USA.
Wei R ChenStephenson School of Biomedical Engineering, University of Oklahoma, Norman, OK 73104, USA.
Xiao-Hong SunOklahoma Medical Research Foundation, Program in Arthritis and Clinical Immunology, 825 NE 13Street, Oklahoma City, OK 73104, USA.
Oklahoma Medical Research Foundation · USUniversity of Oklahoma · USAgricultural Research Service · US

Funding

Exploring the thymic origin of group 2 innate lymphoid cellsR01AI126851 · NIAID · OKLAHOMA MEDICAL RESEARCH FOUNDATION · PI SUN, XIAO-HONG · 2016 to 2020
$2.7M
Exploring the thymic origin of group 2 innate lymphoid cellsR56AI126851 · NIAID · OKLAHOMA MEDICAL RESEARCH FOUNDATION · PI SUN, XIAO-HONG · 2021 to 2021
$618k
5-Laser Cytek Aurora Spectral Flow CytometerS10OD028479 · OD · OKLAHOMA MEDICAL RESEARCH FOUNDATION · PI THOMPSON, LINDA F · 2020 to 2020
$317k
NIAID NIH HHS R01 AI126851NIAID NIH HHS R56 AI126851NIH HHS S10 OD028479
6 · The paper itself

Abstract

The thymus has a high capacity to support the differentiation of ILCs, especially when E protein transcription factors are ablated. Whether it contributes to the homeostasis of ILC pools in tissues is not clear. Single-cell RNA sequencing analysis shows a substantial amount of ILC precursors in wild type but not athymic nude blood. The precursors express CD3 intracellularly (ic) but not on the surface. The abundance of Lin

Indexed as

Components of the immune systemImmunologyOmicsTranscriptomics

Identifiers

PMID35118353
PMCPMC8792071
OpenAlexW4206714858

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.