Evidence map›Paper›PMID 35118319›Full record

ArticleMediastinum (Hong Kong, China)2021

Five years of thoracic endoscopy unit activity on lung cancer staging: how teamwork can improve the outcomes.

Filippo Tommaso Gallina, Daniela Assisi, Daniele Forcella, Federico Pierconti, Paolo Visca, Enrico Melis, Francesco Facciolo

Open access · diamondAbstract read
In one paragraph

Article in Mediastinum (Hong Kong, China), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Filippo Tommaso GallinaThoracic Surgery, IRCCS - Regina Elena National Cancer Institute, Rome, Italy.
Daniela AssisiDigestive Endoscopy Unit, IRCCS - Regina Elena National Cancer Institute, Rome, Italy.
Daniele ForcellaThoracic Surgery, IRCCS - Regina Elena National Cancer Institute, Rome, Italy.
Federico PiercontiAnesthesiology and Intensive Care Unit, IRCCS - Regina Elena National Cancer Institute, Rome, Italy.
Paolo ViscaPathology Unit, IRCCS - Regina Elena National Cancer Institute, Rome, Italy.
Enrico MelisThoracic Surgery, IRCCS - Regina Elena National Cancer Institute, Rome, Italy.
Francesco FaccioloThoracic Surgery, IRCCS - Regina Elena National Cancer Institute, Rome, Italy.
Istituti di Ricovero e Cura a Carattere Scientifico · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRegarding the staging of mediastinal lymph nodes before lung cancer surgery, Endobronchial Ultrasound Transbronchial Needle Aspirations (EBUS-TBNA) have proven to be highly sensitive and specific as well as safe. Endoscopic Ultrasound Fine Needle Aspirations (EUS-FNA) plays an important role in the diagnosis and staging of thoracic diseases, including lung cancer. In this study we analysed all patients underwent endoscopic procedures in our endoscopic mediastinal ultrasound unit.

methodsBetween January 2013 and February 2018, we performed a total of 929 endoscopic procedures, 432 EBUS-TBNA and 497 EUS-FNA. Biopsy was performed at the following mediastinal sites: station 7 in 642 cases, at stations 8 and 9 in 211 cases; at station 3P and 4L in 27 and 114 cases respectively; with EUS we were able to perform biopsy at station 5 in 52 cases.

resultsA total of 841 patients showed a diagnosis of cancer: non-small cell lung cancer (NSCLC) in 645 patients, SCLC in 190 patients, neuroendocrine tumour in 5 patients and one patient with mesothelioma. 88 patients were negative for cancer. In terms of sensitivity, specificity and accuracy, the association between EUS-FNAb and EBUS-TBNAb showed a better quality on diagnosis compared to single procedures. EUS-FNA and EBUS-TBNA are safe, feasible, and highly sensitive techniques.

conclusionsAn endoscopic mediastinal ultrasound unit allows to perform a higher number of endoscopic procedures and improved the sensitivity and the accuracy of the minimally invasive hilar-mediastinal staging.

Indexed as

EBUS-TBNAbEUS-FNAblung cancerlung cancer stagingMediastinal lymph nodesthoracic endoscopy

Identifiers

PMID35118319
PMCPMC8794365
OpenAlexW3163240569

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.