ReviewMediastinum (Hong Kong, China)2020
Clinical approach to childhood mediastinal tumors and management.
Review in Mediastinum (Hong Kong, China), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 27 citations in OpenAlex.
- Thoracoscopic management of mediastinal tumors in children: a single-center experience with mid-term outcomes.BMC pediatrics · 2026Article
- Subxiphoid thoracoscopic resection of anterior mediastinal tumors in children: preliminary clinical experience.Journal of cardiothoracic surgery · 2026Observational
- Giant Mediastinal Teratoma in a Child: A Case Report With a Brief Review of the Literature.Clinical case reports · 2026Article
- Comparison of open, thoracoscopic, and robotic approaches for pediatric mediastinal tumor resection.Journal of robotic surgery · 2025Article
- Awake thoracoscopic mediastinal biopsy in a teenager: a case report.Journal of pediatric surgery case reports · 2025Article
- A rare unusual location of neuroblastoma in theanterior-middle mediastinum in infant: A case report and literature review.Radiology case reports · 2025Article
- Thoracoscopic Resection of a Mediastinal Mature Cystic Teratoma in a Two-month-Old Infant: A Case Report and Literature Review.Pediatric health, medicine and therapeutics · 2025Article
- Infant with lower extremity weakness.Journal of the American College of Emergency Physicians open · 2024Article
- Airway Management for Massive Anterior Mediastinal Tumor Resection in an Infant: A Strategy Involving Spontaneous Breathing-Preserving Endotracheal Intubation under Intravenous Anesthesia.Case reports in pediatrics · 2024Article
- Approach to Imaging of Mediastinal Masses.Diagnostics (Basel, Switzerland) · 2023Review
- Mediastinal lesions in children.World journal of clinical cases · 2023Review
- Giant mediastinal teratoma in a young infant: a case report.Mediastinum (Hong Kong, China) · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Mediastinal tumours are not uncommon in paediatric population and often pose a diagnostic challenge. They include a variety of entities including developmental, inflammatory, infectious and neoplastic; most are malignant. These lesions can be classified based on imaging according to the specific compartment (anterior, middle and posterior), generating a focused differential diagnosis. This combined with a rational, clinically oriented approach based on patient's history, focused physical examination, age, gender, symptoms, signs, anatomic localization, imaging characteristics and laboratory investigations including tumor markers paves way to a presumptive diagnosis guiding additional and prudent investigations. For example, a suspicion of lymphoma should be kept in a child presenting with a neck mass and superior vena cava syndrome. Neuroblastoma should be suspected among children younger than 5 years old with a posterior mediastinal mass. Such a structured approach along with histopathology will lead to an exact diagnosis. Surgery remains the mainstay of treatment of most benign and malignant non-lymphoid tumours. For optimal management, a combined modality of treatment incorporating chemotherapy and radiotherapy is often required in malignant tumours and is associated with high survival rates in these patients. In the present article, we review the approach to evaluation of mediastinal masses in childhood from a clinical perspective.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.