Evidence map›Paper›PMID 35118187›Full record

ArticleSSM - population health2022

Rural/urban dwelling across the life-course and late-life cognitive ability in Mexico.

Joseph L Saenz, Brian Downer, Marc A Garcia, Rebeca Wong

Abstract read
In one paragraph

Article in SSM - population health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Young adult urbanicity, late midlife neighborhood disadvantage, and cognitive functioning in community-dwelling older men.The journals of gerontology. Series B, Psychological sciences and social sciences · 2026
    Article
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  3. Degree of rurality moderates the association of sedentary time with cognitive function in rural patients with cardiac diseases and depressive symptoms.The Journal of rural health : official journal of the American Rural Health Association and the National Rural Health Care Association · 2025
    Article
  4. Article
  5. Lifespan exposures to rural-urban conditions and later-life cognitive function.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025
    Article
  6. Family Size Across the Life Course and Cognitive Decline in Older Mexican Adults.The journals of gerontology. Series B, Psychological sciences and social sciences · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Joseph L SaenzUniversity of Southern California, Leonard Davis School of Gerontology, 3715 McClintock Ave, Los Angeles, CA, 90089, USA.
Brian DownerUniversity of Texas Medical Branch, Division of Rehabilitation Sciences, 301 University Blvd, Galveston, TX, 77555, USA.
Marc A GarciaSyracuse University, Department of Sociology and Maxwell School of Citizenship & Public Affairs, 900 South Crouse Ave, Syracuse, NY, 13244, USA.
Rebeca WongUniversity of Texas Medical Branch, Department of Preventive Medicine and Population Health, 301 University Blvd, Galveston, TX, 77555, USA.

Funding

The Mexican Health and Aging Study - IIR01AG018016 · NIA · UNIVERSITY OF TEXAS MED BR GALVESTON · PI Rebeca Wong · 1999 to 2026
$22.6M
The influence of social and cultural context on life course pathways for Alzheimer's disease, related dementias, and care resources for older Mexican adultsRF1AG068988 · NIA · UNIVERSITY OF TEXAS MED BR GALVESTON · PI DOWNER, BRIAN GREGORY · 2021 to 2021
$1.0M
Education and the Life-Course Pathways of Cognitive Impairment, Dementia, and Cognitive Decline in the United States and MexicoR00AG058799 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI SAENZ, JOSEPH · 2020 to 2022
$745k
NIA NIH HHS R00 AG058799NIA NIH HHS R01 AG018016NIA NIH HHS RF1 AG068988
6 · The paper itself

Abstract

backgroundUrban advantages in older adults' cognitive function have been observed. Less is known about early-life urban dwelling and late-life cognition. We evaluate how rural/urban dwelling throughout life and rural to urban shifts in life relate with cognition in Mexico, a country experiencing aging and urbanization.

methodsData came from the 2003 and 2012 Mexican Health and Aging Study (n = 12,238 adults age 50+). Early-life urban dwelling was self-reported. Late-life urban dwelling was based on population size of respondents' community of residence (community 2500+ people) at the time of survey. Cognitive function was measured across several cognitive tasks. We assess differences in baseline cognitive function and nine-year decline across groups using a latent change score model.

resultsCross-sectionally, compared to always rural dwellers, rural-urban transitions were associated with cognitive benefits, though individuals residing in urban areas continuously through life exhibited the highest levels of cognitive function (

conclusionsEarly- and late-life urban dwelling may result in cognitive advantages for older Mexican adults. Clinicians should consider where individuals resided throughout life to better understand a patient's likelihood of experiencing poor cognitive outcomes.

Indexed as

AgingCognitive declineEducationLatin AmericaMexicoMHASRural/urban

Identifiers

PMID35118187
PMCPMC8800130

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.