ArticleSkin appendage disorders2022
Two Cases of Paradoxical Nonscarring Alopecia after Mesotherapy with Dutasteride.
Article in Skin appendage disorders, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed, 12 citations in OpenAlex.
- Intradermal Injections of 10% Glucose (Sihler G) for Scalp Hair Regrowth: A Randomized, Evaluator-Blinded Pilot Study.Aesthetic plastic surgery · 2026Trial
- Alopecia Induced by Cosmetic Injection Procedures: A Comprehensive Review.Aesthetic plastic surgery · 2026Review
- Outcomes of androgenetic alopecia treated with dutasteride mesotherapy: A case series.JAAD case reports · 2024Article
- Mesotherapy as a Promising Alternative to Minoxidil for Androgenetic Alopecia: A Systematic Review.Cureus · 2024Review
- Paradoxical Nonscarring Alopecia Following Mesotherapy with Dutasteride: A Case Series.International journal of trichologyArticle
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Authors and funding
5 authors at 1 institution in 1 country.
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Abstract
Alopecia after mesotherapy with dutasteride is an extremely rare complication. Dutasteride is a second-generation 5a-reductase enzyme inhibitor that decreases serum dihydrotestosterone levels by 90%. It inhibits both type 1 and 2 enzymes, whereas finasteride inhibits only type 2. Mesotherapy with dutasteride is a novel treatment for hair fall which involves microinjection of the drug into the dermis with negligible systemic absorption. Frequent mild transitory side effects in the site of injection are described in medical literature, but few cases of secondary alopecia have been reported. This stands out given that mesotherapy is becoming such an increasingly common procedure with a great number of patients treated with this technique. We present 2 cases of patchy alopecia after mesotherapy with dutasteride in a male and a female with androgenetic alopecia. One of them developed skin atrophy on the affected areas without improvement at short term follow-up. These cases highlight the possible paradoxical side effects of mesotherapy as a therapeutic technique for hair loss.
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