ReviewFrontiers in pediatrics2021
Does Orthokeratology Wearing Affect the Tear Quality of Children?
Review in Frontiers in pediatrics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06023108 (A Single Center,Randomized,Controlled Trial Assessing the Effects of Spectacles or Orthokeratology on Dry Eye Parameters in Children and Adolescents.), which is not on this map. Cited by 8 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Single Center,Randomized,Controlled Trial Assessing the Effects of Spectacles or Orthokeratology on Dry Eye Parameters in Children and Adolescents.
Who cites it
8 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.
- Orthokeratology in controlling myopia of children: a meta-analysis of randomized controlled trials.BMC ophthalmology · 2023Pooled it
- Development and validation of a risk prediction model for dry eye disease in myopic children.Frontiers in medicine · 2026Article
- Standardized Corneal Topography-Driven AI for Orthokeratology Fitting: A Hybrid Deep/Machine Learning Approach With Enhanced Generalizability.Translational vision science & technology · 2025Article
- Peripheral Defocus in Orthokeratology Myopia Correction: Systematic Review and Meta-Analysis.Journal of clinical medicine · 2025Review
- A deep learning-assisted automatic measurement of tear meniscus height on ocular surface images and its application in myopia control.Frontiers in bioengineering and biotechnology · 2025Article
- Article
- Blinking characteristics analyzed by a deep learning model and the relationship with tear film stability in children with long-term use of orthokeratology.Frontiers in cell and developmental biology · 2024Article
- Short-term application of diquafosol ophthalmic solution benefits children with dry eye wearing orthokeratology lens.Frontiers in medicine · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Orthokeratology is currently known as one of the most effective methods of myopia control in the process of rapid deterioration of the global myopia prevalence. As orthokeratology is widely used, it is necessary to evaluate its complications reasonably and accurately. Eye surface problems in children, such as dry eyes, have received increasing attention. At present, there is no conclusive evidence on how orthokeratology affects the ocular surface, especially the tears. To our knowledge, this is the first study to explore the relationship between orthokeratology lenses and tears through meta-analysis. However, it is still challenging to get a convincing conclusion and a higher level of evidence in this meta-analysis. Reasons for this include limitation of study design, lack of clarity on important confounding factors, lack of appropriate statistical tools, and other biases. This paper will analyze the dilemma existing in the current research from different perspectives to provide meaningful information for future studies in this field.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.