Evidence map›Paper›PMID 35118020›Full record

ReviewJournal of lipid and atherosclerosis2022

Metabolism and Health Impacts of Dietary Sugars.

Yasmine Henna Alam, Raymond Kim, Cholsoon Jang

Abstract readReview
In one paragraph

Review in Journal of lipid and atherosclerosis, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Amazon fig (Food chemistry: X · 2025
    Article
  9. Review
  10. Review
  11. Article
  12. Gut microbiota, nutrients, and depression.Frontiers in nutrition · 2025
    Review
  13. Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Review
  19. Article
  20. Metabolite Changes ofMetabolites · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Yasmine Henna AlamDepartment of Biological Chemistry, University of California Irvine, Irvine, CA, USA.ORCID https://orcid.org/0000-0003-4973-6302
Raymond KimDepartment of Biological Chemistry, University of California Irvine, Irvine, CA, USA.ORCID https://orcid.org/0000-0003-4528-3481
Cholsoon JangDepartment of Biological Chemistry, University of California Irvine, Irvine, CA, USA.ORCID https://orcid.org/0000-0001-6651-4213

Funding

The Southernearch Center for ALPD and CirrhosisP50AA011999 · NIAAA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI ANNA S. GUKOVSKAYA · 1999 to 2026
$45.8M
Elucidating dietary fructose and alcohol interactions during liver cancer developmentR01AA029124 · NIAAA · UNIVERSITY OF CALIFORNIA-IRVINE · PI JANG, CHOLSOON · 2021 to 2025
$2.0M
NIAAA NIH HHS P50 AA011999NIAAA NIH HHS R01 AA029124
6 · The paper itself

Abstract

Consumption of excessive amounts of added sugars and their effects on human health has been a major concern in the last several decades. Epidemiological data suggest that the incidence of metabolic disorders, such as obesity, nonalcoholic fatty liver disease, cardiovascular disease and diabetes, has increased due to chronic surplus consumption of these sugars. While many of these sugars have been isolated and studied for centuries, their health impacts and exact underlying mechanisms are still unclear. In this review, we discuss the pathophysiological role of 6 major simple sugars present in the human diet and the biochemical and molecular pathways related to their metabolism by different organs and gut microbiota, with a focus on the most recent investigations.

Indexed as

ArabinoseFructoseGalactoseGlucoseMannoseXylose

Identifiers

PMID35118020
PMCPMC8792817

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.