Evidence map›Paper›PMID 35117966›Full record

ReviewTranslational cancer research2020

Older breast cancer undertreatment: unconscious bias to undertreat-potential role for the international geriatric radiotherapy group?

Nam P Nguyen, Ulf Karlsson, Eromosele Oboite, Julio Alvarenga, Juan Godinez, Alice Zamagni, Micaela Motta, Satya Bose, Vincent Vinh-Hung

Abstract readReview
In one paragraph

Review in Translational cancer research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Nam P NguyenDepartment of Radiation Oncology, Howard University, Washington, DC, USA.
Ulf KarlssonDeapartment of Radiation Oncology, International Geriatric Radiotherapy Group, Washington, DC, USA.
Eromosele OboiteDepartment of Radiation Oncology, Howard University, Washington, DC, USA.
Julio AlvarengaDivision of Hematology Oncology, Fox Chase Cancer Center, Philadelphia, PA, USA.
Juan GodinezDepartment of Radiation Oncology, Choice Cancer Care at Wise Hospital, Decatur, TX, USA.
Alice ZamagniRadiation Oncology Center, Department of Experimental, Diagnostic, and Specialty Medicine, Sant'Orsola-Malpighi Hospital, University of Bologna, Bologna, Italy.
Micaela MottaDepartment of Radiation Oncology, Hospital Papa Giovanni XXIII, Bergamo, Italy.
Satya BoseDepartment of Radiation Oncology, Howard University, Washington, DC, USA.
Vincent Vinh-HungDepartment of Radiation Oncology, University of Martinique, Martinique, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The prevalence of breast cancer increases with age. Older breast cancer patients often present with locally advanced disease at presentation because mammography, which diagnosed early stage disease, is not recommended after the age of 75. In addition, they are often undertreated even when they are physically fit and have non-metastatic disease. As a result, survival is often poor. Physicians bias may be a factor in their undertreatment and lack of representation in prospective clinical trials. Physicians should be educated that chronological age is not a contraindication to curative treatment for older breast cancer patients. As a research group devoted to older cancer patients, women, and minorities, the International Geriatric Radiotherapy Group (IGRG) plans to conduct prospective trials to assess biomarkers for frailty, the controversial issue of mammography for older breast cancer patients, and the incorporation of frailty index for curative breast cancer treatment. The data obtained may help to decrease physician bias and to establish future guidelines for older breast cancer patients treatment.

Indexed as

breast cancerdiscriminationElderlyundertreatment

Identifiers

PMID35117966
PMCPMC8798381

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.