Evidence map›Paper›PMID 35117949›Full record

ReviewTranslational cancer research2020

The management of elderly patients with brain metastases from breast cancer.

Henry Ruiz-Garcia, Lina Marenco-Hillembrand, Jennifer L Peterson, Katherine Tzou, Timothy D Malouff, Kaisorn L Chaichana, Daniel M Trifiletti, Laura Vallow

Open access · diamondAbstract readReview
In one paragraph

Review in Translational cancer research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 100% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Henry Ruiz-GarciaDepartment of Radiation Oncology, Mayo Clinic, Jacksonville, Florida, USA.
Lina Marenco-HillembrandDepartment of Neurological Surgery, Mayo Clinic, Jacksonville, Florida, USA.
Jennifer L PetersonDepartment of Radiation Oncology, Mayo Clinic, Jacksonville, Florida, USA.
Katherine TzouDepartment of Radiation Oncology, Mayo Clinic, Jacksonville, Florida, USA.
Timothy D MalouffDepartment of Radiation Oncology, Mayo Clinic, Jacksonville, Florida, USA.
Kaisorn L ChaichanaDepartment of Neurological Surgery, Mayo Clinic, Jacksonville, Florida, USA.
Daniel M TrifilettiDepartment of Radiation Oncology, Mayo Clinic, Jacksonville, Florida, USA.
Laura VallowDepartment of Radiation Oncology, Mayo Clinic, Jacksonville, Florida, USA.
Mayo Clinic in Florida · USJacksonville College · USWinnMed · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Breast cancer is the most common type of malignancy diagnosed in women worldwide, as well as the second most common cause of metastatic brain lesions in the general population. Most breast cancer patients enrolled in clinical trials are relatively young. Elderly patients, as compared to their younger counterparts, pose unique clinical scenarios because there is limited data in this subpopulation of patients with brain metastases from breast cancer. Elderly patients are commonly treated with less aggressive therapies, perhaps due to comorbid conditions, patient preference, or other age-related concerns. Current treatment modalities offering more favorable toxicity profiles, along with more accurate prognosis, can represent an opportunity to offer improved care for this patient population. From the few efforts studying brain metastatic disease in the elderly, it is be possible to infer that age alone may not play an independent role in treatment selection and that a patient-specific evaluation and ultimate clinical judgment should guide clinical decision-making.

Indexed as

Brain metastasesbreast cancerelderlymanagementradiationradiotherapy

Identifiers

PMID35117949
PMCPMC8798207
OpenAlexW2967992442

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.