Evidence map›Paper›PMID 35117815›Full record

ArticleTranslational cancer research2020

A randomized controlled trial of Chinese traditional medicine Dachengqi Decoction in the treatment of postoperative intestinal function recovery.

Yuwen Luo, Xingyu Feng, Deqing Wu, Junjiang Wang, Zejian Lyv, Jiabin Zheng, Kheng Tian Lim, Yong Li

Open access · diamondAbstract read
In one paragraph

Article in Translational cancer research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
0.4field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Pooled it
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Yuwen Luo *Second School of Clinical Medicine, Southern Medical University, Guangzhou, China.
Xingyu Feng *Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, China.
Deqing WuGuangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, China.
Junjiang WangGuangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, China.
Zejian LyvGuangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, China.
Jiabin ZhengGuangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, China.
Kheng Tian LimDepartment of Surgery, Khoo Teck Puat Hospital, Singapore, Singapore.
Yong LiSecond School of Clinical Medicine, Southern Medical University, Guangzhou, China.
Guangdong Academy of Medical Sciences · CNKhoo Teck Puat Hospital · SG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIntestinal dysfunction is not conducive to the recovery of patients after surgery. It is particularly important to restore the intestinal function as soon as possible. In recent years, ultrasonic drug penetration therapy as a new type of non-invasive therapy has been used to solve this problem, but its efficacy has not been confirmed.

methodsSingle-centre, parallel, randomized controlled clinical trial in China that included 184 patients undergoing laparoscopic gastrointestinal surgery. Ninety-one participants were randomly assigned to low-frequency ultrasound and electric pulses for transdermal drug delivery with Dachengqi Decoction (DCQD) (intervention group), and 90 were assigned to the control group after laparoscopic gastrointestinal surgery. The primary outcome was time to first flatus after surgery (by patient's subjective feeling). Secondary outcomes assessed the recovery time of bowel movement, time of the first defecation, postoperative gastrointestinal complications (e.g., nausea, vomit, and bloating), days of hospitalization and treatment costs.

resultsOf 184 patients, 181 (98.4%) completed the trial. The sociodemographic characteristics and efficiency data were comparable in the two groups at baseline. The intervention group had a shorter mean time of bowel movement recovery than the control group [29.4 h (IQR, 22.0-35.0 h)

conclusionsLow-frequency ultrasound and electric pulses for transdermal drug delivery with DCQD can shorten the time of bowel movement recovery and accelerate first anal exhaust after laparoscopic gastrointestinal surgery. TRAIL REGISTRATION: Chictr.org.cn Identifier: ChiCTR-IPR-17013630.

Indexed as

Dachengqi decoctionintestinal function recoveryLow-frequency ultrasoundtransdermal drug delivery

Identifiers

PMID35117815
PMCPMC8797330
OpenAlexW3048814595

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.