Evidence map›Paper›PMID 35117645›Full record

ArticleTranslational cancer research2020

Type 2 diabetes mellitus does not increase the risk of multiple myeloma: a systematic review and meta-analysis.

Chenlu Zhang, Yuou Sha, Haiyan Liu, Dan Guo, Yijing Jiang, Lemin Hong, Lili Shi, Hongming Huang

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Translational cancer research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Chenlu Zhang *Department of Hematology, The Affiliated Hospital of Nantong University, Nantong 226001, China.
Yuou Sha *Department of Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430074, China.
Haiyan Liu *Department of Hematology, The Affiliated Hospital of Nantong University, Nantong 226001, China.
Dan GuoDepartment of Hematology, The Affiliated Hospital of Nantong University, Nantong 226001, China.
Yijing JiangDepartment of Hematology, The Affiliated Hospital of Nantong University, Nantong 226001, China.
Lemin HongDepartment of Hematology, The Affiliated Hospital of Nantong University, Nantong 226001, China.
Lili ShiDepartment of Medical Informatics, Medical School of Nantong University, Nantong 226001, China.
Hongming HuangDepartment of Hematology, The Affiliated Hospital of Nantong University, Nantong 226001, China.
Nantong University · CNAffiliated Hospital of Nantong University · CNHuazhong University of Science and Technology · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEpidemiological studies have shown that patients with type 2 diabetes mellitus (T2DM) are at a higher risk of secondary tumors. However, no consensus has been made about whether T2DM can increase the risk of multiple myeloma (MM).

methodsWe searched the databases of PubMed, Cochrane Library and EMBASE and cross-checked the bibliography. Data quality was assessed using the Newcastle-Ottawa scale (NOS). Heterogeneity was calculated as the odds ratio (OR) using a random-effects model. Data were analyzed using Stata version 12.0 software.

resultsA total of 13 articles were selected into this meta-analysis. Initially, we found that diabetic patients had a higher risk of myeloma than non-diabetic patients (OR =1.60, 95% CI: 1.13-2.26, I

conclusionsT2DM is not a risk factor for the increased incidence of MM, a finding that should be validated with more strictly designed randomized controlled trials (RCTs).

Indexed as

carcinogenic riskMeta-analysismultiple myeloma (MM)type 2 diabetes mellitus (T2DM)

Identifiers

PMID35117645
PMCPMC8798954
OpenAlexW3013611021

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.