ArticleTranslational cancer research2020
Prognosis of stage III cervical cancer: a two-way outcome study.
Article in Translational cancer research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
5 citing papers in PubMed.
- LncRNA STARD7-AS1 suppresses cervical cancer cell proliferation while promoting autophagy by regulating miR-31-5p/TXNIP axis to inactivate the mTOR signaling.Journal of gynecologic oncology · 2024Article
- Investigating and Analyzing Prognostic Factors and Their Impact on Recurrent Cervical Cancers.Cureus · 2024Review
- An overview of the past decade of bufalin in the treatment of refractory and drug-resistant cancers: current status, challenges, and future perspectives.Frontiers in pharmacology · 2023Review
- A model to guide the management and decision of re-planning during radiotherapy for cervical cancer.Translational cancer research · 2021Article
- Autophagy-related long non-coding RNA signature for potential prognostic biomarkers of patients with cervical cancer: a study based on public databases.Annals of translational medicine · 2021Article
Corrections and comments
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCervical cancer is the second most common female malignancy worldwide, and the prognosis of patients with the locally advanced stage is poor, with a high risk of recurrent. This study aimed to explore the effect factors that influence the overall survival (OS), progression-free survival (PFS), and quality of life in patients with stage III cervical cancer.
methodsA two-way follow-up method was utilized to collect information from patients with stage III cervical cancer. Survival analyses were performed by the Kaplan-Meier method and Cox regression model. Multiple linear regression was used to analyze the factors related to quality of life.
resultsFour hundred and sixty subjects were enrolled in this study. The median follow-up time was 28 months (range, 1-51 months). The 3-year OS and PFS rates were 69.0% and 55.0%, respectively. Primiparous age above 30 years, age at diagnosis below 40 years, lymph node metastasis, non-squamous cell carcinoma, and larger tumors were risk factors of OS and PFS, while the protective factors were weight loss, good mental status, and standardized treatment. The quality of life was better in patients with the following characteristics: younger age at diagnosis, active review according to medical orders, and earlier return to society.
conclusionsPrimiparous age above 30 years was a poor prognostic factor for OS, PFS, and quality of life. The common factors relevant to prognosis were confirmed to be significant.
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