Evidence map›Paper›PMID 35117611›Full record

ArticleTranslational cancer research2020

Prognosis value of liver stiffness measurements by 2D-SWE in primary HBV-positive hepatocellular carcinoma following radiofrequency ablation.

Xinxin Xie, Yongqiang Yu

Open access · diamondAbstract read
In one paragraph

Article in Translational cancer research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.

  1. Guideline
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Xinxin XieUltrasound Department, The First Affiliated Hospital of Anhui Medical University, Hefei 230000, China.
Yongqiang YuRadiology Department, The First Affiliated Hospital of Anhui Medical University, Hefei 230000, China.
Anhui Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLiver fibrosis is closely associated with the occurrence of hepatocellular carcinoma (HCC), which can be evaluated by liver stiffness measurements (LSM). The clinical significance of LSMin patient with hepatitis B virus (HBV) related HCC underwent radiofrequency ablation (RFA) was evaluated.

methodsTotal of 273 patients underwent RFA for primary HBV-positive HCC were included. LSM values were measured by using by 2D-shear wave elastography (2D-SWE) prior to RFA. The relationship between pretreatment LSM value and survival outcome was evaluated. The cutoff value for LSM to predict survival outcome was determined by receiver operating characteristic (ROC) curve analysis.

resultsAt the endpoint of this study, 88 (32.2%) and 73 (26.7%) patients out of all 273 patients studied had died and recurrent, respectively. All patients were divided into two groups based on the cutoff value (13.4 kPa) of LSM. Patients with a LSM ≥13.4 kPa had lower mean overall survival (62.5

conclusionsLSM measured by 2D-SWE can sever as an independent prognostic indictor for patients undergoing RFA for HBV-positive HCC.

Indexed as

hepatitis B virus (HBV)hepatocellular carcinoma (HCC)Liver stiffnessprognosisradiofrequency ablation

Identifiers

PMID35117611
PMCPMC8798438
OpenAlexW3014052410

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.