ArticleTranslational cancer research2020
Clinical features and prognosis of primary tracheal small cell carcinoma: a population-based analysis.
Article in Translational cancer research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed, 8 citations in OpenAlex.
- Primary tracheal small cell carcinoma: A case report and discussion of its surgical and oncological management.JTCVS techniques · 2025Article
- Clinical Manifestation and Multidisciplinary Treatment Approaches for Primary Tracheal Carcinoma in Bangladesh: A Clinical and Therapeutic Review of 13 Patients.Cancer reports (Hoboken, N.J.) · 2024Observational
- Case report: A novel perspective on the treatment of primary tracheal small cell carcinoma: a patient's experience with immuno-combined EP therapy and literature review.Frontiers in immunology · 2024Review
- Article
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Authors and funding
10 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPrimary tracheal small cell carcinoma (SCC) is an uncommon malignancy; therefore, its clinical features and prognosis are still unclear.
methodsWe used the population-based Surveillance, Epidemiology, and End Results (SEER) database to elucidate the clinical features and prognosis of primary tracheal SCC. The clinical features were assessed by using the chi-square test. Overall survival (OS) was computed using the Kaplan-Meier method, and a Cox proportional hazards analysis was performed to evaluate the prognostic factors.
resultsFrom 1973 to 2015, 1,392 primary tracheal tumor cases were reported in the SEER database, 75 (5.4%) of which were SCC. Age, sex, race, extent of disease, lymph node involvement, surgery and radiation treatment were similar between patients with SCC and those with squamous cell carcinoma (SQC), but patients with SCC were more likely to receive chemotherapy (65.8%
conclusionPrimary tracheal SCC is a rare carcinoma with a poor prognosis. Age and lymph node involvement are independent prognostic factors of SCC.
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