ArticleTranslational cancer research2020
Applied research of a four-dimensional CT localization technique in radiotherapy and treatment planning for early lung cancer.
Article in Translational cancer research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Improving motion management in radiation therapy: findings from a workshop and survey in Australia and New Zealand.Physical and engineering sciences in medicine · 2024Article
- Intraoperative localization in minimally invasive surgery for small pulmonary nodules: a retrospective study.Translational cancer research · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTo study the feasibility of target contouring and the potential benefits to radiotherapy of four-dimensional computed tomography (4D-CT) for early stage lung cancer.
methodsWe applied Brilliance CT to scan 24 lung cancer patients for 4D localization. Treatment plannings based on different breath phase CT images were designed in the Monaco 5.2 treatment planning system. Different planning was compared to find the difference of target volume, center, and dose.
resultsTarget volume composed of 10-breath phases (Sum) was considered as the reference volume, which was slightly larger than the volume contouring obtained by the maximum intensity projection (Mip) and extreme phase images (Exs). Target centers for Sum, Mip and Exs of CT images showed little deviation in the X, Y and Z directions. The V20 and V5 for the 4D-CT-based treatment plan showed a markedly lower dose delivered to normal tissues than those based on 3D-CT.
conclusionsFor target contouring, a target contouring by 10-breath phases was superior to Mip and Exs. As the gross target volume (GTV) contouring obtained by the maximum intensity projection and extreme phase were similar to that of the reference target, they can support the contouring target and reduce the time and work. Treatment plan comparisons indicated that normal lung tissues received a remarkably lower dose when a 4D-CT-based plan was used.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.