Evidence map›Paper›PMID 35117155›Full record

ArticleTranslational cancer research2020

Relationship between histogram metrics of pharmacokinetic parameters of DCE-MRI and histological phenotype in breast cancer.

Guocai Yang, Jing Yang, Hui Xu, Qingxin Zhang, Yonghong Qi, Aiju Zhang

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Translational cancer research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.1field-weighted citation impact, top 54% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Guocai YangMR Laboratory of Qinghai People's Hospital, Xining 810007, China.
Jing YangMR Laboratory of Qinghai People's Hospital, Xining 810007, China.
Hui XuMR Laboratory of Qinghai People's Hospital, Xining 810007, China.
Qingxin ZhangMR Laboratory of Qinghai People's Hospital, Xining 810007, China.
Yonghong QiMR Laboratory of Qinghai People's Hospital, Xining 810007, China.
Aiju ZhangMR Laboratory of Qinghai People's Hospital, Xining 810007, China.
Qinghai No.3 People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTo investigate the correlation between quantitative pharmacokinetic parameters and clinicopathological prognostic biomarkers including estrogen receptor (ER), progesterone receptor (PR), human epidermal growth factor receptor 2 (HER2), and MiB1 (Ki-67) in patients with breast cancer, the image histogram analysis was performed on dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI).

methodsThe reference region model (RRM) was used to calculate the quantitative permeability parameters, including reference region volume transfer constant (

resultsAll the histogram metrics of

conclusionsHistogram analysis on quantitative pharmacokinetic breast parameters using DCE-MRI improves the performance in differentiation of histological phenotypes of breast cancer.

Indexed as

Breast cancerdynamic contrast-enhanced magnetic resonance imaging (DCE-MRI)histogram analysishistological phenotypepharmacokinetic parameter

Identifiers

PMID35117155
PMCPMC8798285
OpenAlexW2999455438

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.