Evidence map›Paper›PMID 35117153›Full record

ArticleTranslational cancer research2020

Prognostic significance of artemin in gastric cancer and its role in tumorigenesis.

Xiaoping Jiang, Kai Chen, Kaixi Fan, Jing Guo

Open access · diamondAbstract read
In one paragraph

Article in Translational cancer research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.1field-weighted citation impact, top 59% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 1 country.

Xiaoping Jiang *Department of Respiratory, Shanxian Central Hospital, Heze 274300, China.
Kai Chen *Department of Cardiothoracic Surgery, The 2nd Affiliated Hospital and Yuying Children's Hospital, Wenzhou Medical University, Wenzhou 325027, China.
Kaixi FanDepartment of Oncology, Shandong Cancer Hospital and Institute, Jinan 250117, China.
Jing GuoDepartment of Oncology, Shandong Cancer Hospital and Institute, Jinan 250117, China.
Second Affiliated Hospital & Yuying Children's Hospital of Wenzhou Medical University · CNShandong First Medical University · CNShandong Tumor Hospital · CNXian Central Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAbundant evidence suggests that a neurotrophic factor, artemin (ARTN), is involved in the tumorigenesis and progression in several malignancies. However, the biological functions of ARTN in gastric cancer (GC) remain poorly elucidated.

methodsARTN expression was evaluated by immunohistochemistry in GC tissue, and its clinical and prognosis significance was analyzed. Cell counting kit-8 (CCK-8), transwell chamber assay, and western blot were used to detect the effects of ARTN knockdown on GC cell behavior

resultsARTN was highly expressed in GC tissue, and its positive expression predicted poor prognosis of GC.

conclusionsARTN might be a promising prognostic marker and a potential therapeutic target for GC.

Indexed as

Artemin (ARTN)gastric cancer (GC)prognosissignal transducer and activator of transcription-3

Identifiers

PMID35117153
PMCPMC8797394
OpenAlexW2996568213

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.