Evidence map›Paper›PMID 35116830›Full record

ArticleTranslational cancer research2019

The effect of hericium polysaccharides combined with aspirin on the expression of CD133 and ABCG2 in lung cancer.

Zhansheng Lu, Bo Liu, Qinbing Zhang, Meng Luo, Yongpan Sun

Open access · diamondAbstract read
In one paragraph

Article in Translational cancer research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Zhansheng LuDepartment of Thoracic Surgery, Guizhou Provincial People's Hospital, Guiyang 550000, China.
Bo LiuDepartment of Thoracic Surgery, Guizhou Provincial People's Hospital, Guiyang 550000, China.
Qinbing ZhangDepartment of Thoracic Surgery, Guizhou Provincial People's Hospital, Guiyang 550000, China.
Meng LuoDepartment of Thoracic Surgery, Guizhou Provincial People's Hospital, Guiyang 550000, China.
Yongpan SunDepartment of Thoracic Surgery, Guizhou Provincial People's Hospital, Guiyang 550000, China.
Guizhou Provincial People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe study was designed to investigate the effects of aspirin and hericium polysaccharides (HP) on the expression of CD133 and ABCG2 in lung cancer growth.

methods

resultsAspirin alone, HP alone and combined aspirin and HP inhibited cell proliferation significantly. Western blot results showed that Aspirin alone, HP alone and combined HP and aspirin inhibited the expression levels of CD133 significantly, but HP alone did not inhibit the expression levels of ABCG2. Combined HP and aspirin are synergistic.

conclusionsThe combined effect of aspirin and HP inhibited tumor growth significantly by obstructing CD133 and ABCG2 expression in lung cancer.

Indexed as

ABCG2AspirinCD133hericium polysaccharides (HP)lung cancer

Identifiers

PMID35116830
PMCPMC8799280
OpenAlexW4237851697

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.