Evidence map›Paper›PMID 35116780›Full record

ArticleTranslational cancer research2019

Mengjia Shen, Libo Yang, Ting Lei, Lin Xiao, Li Li, Peichuan Zhang, Weiyi Feng, Feng Ye, Hong Bu

Abstract read
In one paragraph

Article in Translational cancer research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Mengjia ShenLaboratory of Pathology, Clinical Research Center for Breast, West China Hospital, Sichuan University, Chengdu 610041, China.
Libo YangLaboratory of Pathology, Clinical Research Center for Breast, West China Hospital, Sichuan University, Chengdu 610041, China.
Ting LeiLaboratory of Pathology, Clinical Research Center for Breast, West China Hospital, Sichuan University, Chengdu 610041, China.
Lin XiaoLaboratory of Pathology, Clinical Research Center for Breast, West China Hospital, Sichuan University, Chengdu 610041, China.
Li LiLaboratory of Pathology, Clinical Research Center for Breast, West China Hospital, Sichuan University, Chengdu 610041, China.
Peichuan ZhangLaboratory of Pathology, Clinical Research Center for Breast, West China Hospital, Sichuan University, Chengdu 610041, China.
Weiyi FengBig Data Research Center, School of Computer Science and Engineering, University of Electronic Science and Technology of China, Chengdu 610054, China.
Feng YeLaboratory of Pathology, Clinical Research Center for Breast, West China Hospital, Sichuan University, Chengdu 610041, China.
Hong BuLaboratory of Pathology, Clinical Research Center for Breast, West China Hospital, Sichuan University, Chengdu 610041, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBreast cancer is the most commonly diagnosed cancer among women. Although many studies have reported the

methodsA total of 54 female patients diagnosed with breast cancer were enrolled in this study, of which 27 were younger than 40 (study group, mean age 32 years, range, 23-40 years) and 27 were older than 40 (control group, mean age 52 years, range, 41-68 years). Tumor FFPE samples were collected for somatic mutation test, while blood samples or normal tissue were used for germline mutation by both PGM and Miseq platform. All codon exons and functional introns for

resultsIn study group, 14.8% (4/27) and 3.7% (1/27) patients had deleterious

conclusionsOur study found two novel

Indexed as

BRCA1BRCA2early-onset breast cancernext-generation sequencing (NGS)

Identifiers

PMID35116780
PMCPMC8798914

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.