ArticleTranslational cancer research2021
Extraskeletal Ewing's sarcoma: outcomes and CT features of endoceliac lesions.
Article in Translational cancer research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed, 5 citations in OpenAlex.
- Radiological findings in children with primary mediastinal Ewing sarcoma/primitive neuroectodermal tumors: a retrospective case series study.Quantitative imaging in medicine and surgery · 2025Article
- Muscular Cystic Lesions: A Highly Misdiagnosed Extraosseous Ewing Sarcoma: Two Case Reports and Literature ReviewCurrent medical imaging · 2025Review
- Case report: Primary mediastinal Ewing's sarcoma presenting with chest tightness.Frontiers in oncology · 2022Article
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundExtraskeletal Ewing's sarcoma (EES) is one kind of rare malignant tumour which is always misdiagnosed preoperatively, especially for lesions located at endoceliac sites. This study analyse the clinicopathological features and outcomes of EES patients. The basic imaging characteristics of endoceliac lesions are also summarized.
methodsThis study involved EES patients admitted to our centre between January 2000 and January 2020. Clinical data from patients with EES (n=25) and computed tomography (CT) features from endoceliac EES patients with available CT data (n=8) were retrospectively reviewed.
resultsThe sample comprised 18 males and 7 females with a median age of 30 years (range, 1-72 years). Seven patients had EES originating from surface sites and 18 had EES originating from endoceliac sites. The median tumour size was 8.0 cm (range, 2.5-17.0 cm). In total, 20% of patients had distant metastasis at diagnosis. In the univariate analyses, tumour size >8 cm, non-surgical treatment, and regional lymph nodes metastasis were risk factors for poor prognosis of EES. In the multivariate analysis, patients with larger tumour size and regional lymph node metastasis were independent predictors of overall survival (OS). Endoceliac EES cases frequently exhibited lobulated contour (87.5%), absence of calcification (75%), severe necrosis or cystic degeneration (75%), heterogeneous enhancement (100%), moderate enhancement (75%), ill-defined borderline (62.5%), and organ invasion (75%). Half of the patients with endoceliac EES had CT features of lymphadenopathy.
conclusionsComprehensive understanding of the clinicopathological and imaging features of EES is beneficial for diagnosis, development of therapeutic strategies, and accurate prediction of prognosis for this rare malignant tumour.
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