ReviewTranslational cancer research2021
Specific study of biological tumor cytology: a narrative review.
Review in Translational cancer research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed, 2 citations in OpenAlex.
- Recent progress in molecular mechanisms of postoperative recurrence and metastasis of hepatocellular carcinoma.World journal of gastroenterology · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Tumor metastasis is a very complex invasion. The concept of circulating tumor cells (CTCs), which describes the tumor cells diffusing into the blood, is being increasingly recognized for its role in cancer metastasis as well as it is considered the key step of tumor blood metastasis. Epithelial-mesenchymal transition (EMT) is the reverse transition from mesenchymal phenotypes to an epithelial one. Tumor cells undergoing this process have stronger metastatic potential. Though the biological characteristics of CTCs after EMT can help explain the unknown phenomena in tumor metastasis, the biomarkers of CTCs after EMT are not accurate. Also the correlation between CTCs after EMT and the prognosis of patients and the dynamic transformation of cell groups during treatment are not clear. Tumor metastasis initiating cells (MIC), which eventually lead to metastasis in CTCs, are types of cancer stem cells, or at least tumor cells with many stem cell characteristics. Further investigation of the maintenance of tumor stem cell characteristics of CTCs is required. The circulating tumor microemboli (CTM) can prevent CTCs from losing their nests, and the presence of host cells facilitates special metastasis and helps tumor cells escape immune surveillance. In this paper, we reviewed research on the biological cytological characteristics of CTCs in recent years, and provided relevant supporting evidence for monitoring tumor recurrence, assessing patient prognosis, evaluating the sensitivity of anti-tumor biological drugs, and selecting an individualized treatment plan.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.