ArticleTranslational cancer research2021
The predictive and prognostic value of sex in localized colorectal cancer: a SEER-based analysis.
Article in Translational cancer research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 8 citations in OpenAlex.
- Sex Differences in Colorectal Tumor-Associated T-cell Responses.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2026Article
- The Demographic Profile of Colorectal Cancer Patients in Indonesia: Insights from a Single Center Experience and Exploration of Immune Response and Survival Outcomes.F1000Research · 2024Article
- Emergency resection is an independent risk factor for decreased long-term overall survival in colorectal cancer: a matched-pair analysis.World journal of surgical oncology · 2023Article
- Monitoring Metabolic Changes in Response to Chemotherapies in Cancer with Raman Spectroscopy and Metabolomics.Analytical chemistry · 2023Article
- Involvement in treatment decision-making and self-reported efficacy among patients with advanced colorectal cancer: a nationwide multi-center cross-sectional study.Frontiers in oncology · 2023Article
- The Prediction of Survival Outcome and Prognosis Factor in Association with Comorbidity Status in Patients with Colorectal Cancer: A Research-Based Study.Healthcare (Basel, Switzerland) · 2022Article
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAlthough the influence of sex on different cancer survival has been investigated, the predictive and prognostic value of sex in localized colorectal cancer (CRC) still remain controversial.
methodsSurvival was evaluated in patients who diagnosed with localized CRC in the Surveillance, Epidemiology, and End Results (SEER) database between 2004 and 2016. Overall survival (OS) outcomes were estimated with the Kaplan-Meier method, and multivariable Cox regression was used to calculate hazard ratios (HRs) and 95% confidence intervals (CIs).
resultsWe obtained a dataset that included 70,836 males and 69,705 females of localized CRC patients. Compared with males, females more often had age ≥75 years (55.1%
conclusionsIn our study, sex was shown to be a prognostic factor in localized-CRC. In particular, females may benefit more from postoperative chemotherapy than males with T3N0M0 (Stage II) rectal cancer.
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