Evidence map›Paper›PMID 35116422›Full record

ArticleTranslational cancer research2021

Construction of a novel ceRNA network and identification of lncRNA

Song Wang, Xing-Chuan Li, Jia-Rui Zhu, Zhi-Jie Ma, Jun-Tao Ran, Yong-Ning Zhou

Open access · diamondAbstract read
In one paragraph

Article in Translational cancer research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Song WangDepartment of Radiotherapy, The First Hospital of Lanzhou University, Lanzhou, China.
Xing-Chuan LiDepartment of Gastroenterology, The First Hospital of Lanzhou University, Lanzhou, China.
Jia-Rui ZhuCuiying Biomedical Research Center, Lanzhou University Second Hospital, Lanzhou, China.
Zhi-Jie MaDepartment of Anesthesiology, Lanzhou University Second Hospital, Lanzhou, China.
Jun-Tao RanDepartment of Radiotherapy, The First Hospital of Lanzhou University, Lanzhou, China.
Yong-Ning ZhouDepartment of Gastroenterology, The First Hospital of Lanzhou University, Lanzhou, China.
Lanzhou University · CNFirst Hospital of Lanzhou University · CNLanzhou University Second Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundStudies on the interactions of single long non-coding RNA, microRNA, and mRNA have many limitations; therefore, it is necessary to study the complex regulatory network of gastric cancer (GC) pathogenesis systematically.

methodsIn this study, gene and miRNA expression data for GC were downloaded from The Cancer Genome Atlas and used for transcriptome profiling, differential gene analysis, and construction of an lncRNA-miRNA-mRNA regulatory network in conjunction with an online database to identify the key genes and subnetworks in GC pathogenesis. Real-time quantitative polymerase chain reaction was used to detect the expression of hub lncRNAs in 54 paired GC and matched normal mucosal tissues.

resultsWe constructed an lncRNA-miRNA-mRNA competitive endogenous RNA regulatory network containing 1,626 network nodes and 2,704 interactions. LncRNA

conclusionsThis study systematically analysed the lncRNA-miRNA-mRNA regulatory network in GC and identified

Indexed as

ADAMTS9-AS2gene regulatory networkslong noncoding RNAPVT1Stomach neoplasm

Identifiers

PMID35116422
PMCPMC8799272
OpenAlexW3135098323

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.