Evidence map›Paper›PMID 35116327›Full record

ArticleTranslational cancer research2021

The clinical prognostic factors of patients with stage IB lung adenocarcinoma.

Qihai Sui, Jiaqi Liang, Zhengyang Hu, Xinming Xu, Zhencong Chen, Yiwei Huang, Mengnan Zhao, Cheng Zhan, Lin Wang, Zongwu Lin and 1 more

Open access · diamondAbstract read
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Article in Translational cancer research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 1 country.

Qihai Sui *Department of Thoracic Surgery, Zhongshan Hospital, Fudan University, Shanghai, China.
Jiaqi Liang *Department of Thoracic Surgery, Zhongshan Hospital, Fudan University, Shanghai, China.
Zhengyang Hu *Department of Thoracic Surgery, Zhongshan Hospital, Fudan University, Shanghai, China.
Xinming XuSchool of Basic Medical Sciences, Shanghai Medical College, Fudan University, Shanghai, China.
Zhencong ChenDepartment of Thoracic Surgery, Zhongshan Hospital, Fudan University, Shanghai, China.
Yiwei HuangDepartment of Thoracic Surgery, Zhongshan Hospital, Fudan University, Shanghai, China.
Mengnan ZhaoDepartment of Thoracic Surgery, Zhongshan Hospital, Fudan University, Shanghai, China.
Cheng ZhanDepartment of Thoracic Surgery, Zhongshan Hospital, Fudan University, Shanghai, China.
Lin WangDepartment of Thoracic Surgery, Zhongshan Hospital, Fudan University, Shanghai, China.
Zongwu LinDepartment of Thoracic Surgery, Zhongshan Hospital, Fudan University, Shanghai, China.
Qun WangDepartment of Thoracic Surgery, Zhongshan Hospital, Fudan University, Shanghai, China.
Fudan University · CNThe First Affiliated Hospital, Sun Yat-sen University · CNZhongshan Hospital · CNShanghai Medical College of Fudan University · CNSun Yat-sen University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLung adenocarcinoma (ADC) at stage IB has its own prognostic characteristics. This study aimed to investigate the clinical factors that may affect the prognosis of patients with stage IB ADC.

methodsThe data of ADC cases were selected from the Surveillance, Epidemiology, and End Results (SEER) database (2010-2016) and patients in Zhongshan Hospital, Fudan University (Department of Thoracic Surgery, 2015-2016). Kaplan-Meier method was used to obtain the overall survival (OS). Factors that significantly related to the prognosis were evaluated by univariate and multivariate analysis (UVA, MVA) using the Cox model. A nomogram was developed and validated to predict the 3-year OSs of those patients.

results7,605 patients with stage IB ADC were included ultimately and were divided into two groups, a training cohort (n=5,324) and a test cohort (n=2,281). Besides, there was a validation cohort (n=272) for the verification of the nomogram model. Those with significantly older age, male, the white race, lower grades of tumor differentiation, larger tumor size (31-40 mm) without pleural layer (PL) invasion as well as receiving sublobectomy suffered from poorer survival (P<0.001), which were identified as independent factors for stage IB ADC (P<0.001), and according to which, a nomogram model was created.

conclusionsAge, sex, race, histological grade, surgery to the primary site, and tumor size combined with PL invasion were independent risk factors for stage IB ADC, based on which a nomogram was constructed to predict the prognosis.

Indexed as

AJCCLung adenocarcinomaprognosisstage IB

Identifiers

PMID35116327
PMCPMC8799094
OpenAlexW3209372770

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.