Evidence map›Paper›PMID 35116058›Full record

ReviewFrontiers in genetics2021

Emerging Role and Mechanism of circRNAs in Pediatric Malignant Solid Tumors.

Qiyang Shen, Xingyu Liu, Wei Li, Xu Zhao, Tao Li, Kai Zhou, Jianfeng Zhou

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Frontiers in genetics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 54% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Qiyang ShenDepartment of Pediatric Surgery, Children's Hospital of Nanjing Medical University, Nanjing, China.
Xingyu LiuDepartment of Pediatric Surgery, First Affiliated Hospital of Bengbu Medical College, Bengbu, China.
Wei LiDepartment of ENT, Children's Hospital of Nanjing Medical University, Nanjing, China.
Xu ZhaoDepartment of Pediatric Surgery, First Affiliated Hospital of Bengbu Medical College, Bengbu, China.
Tao LiDepartment of Pediatric Surgery, Children's Hospital of Nanjing Medical University, Nanjing, China.
Kai ZhouDepartment of Pediatric Surgery, First Affiliated Hospital of Bengbu Medical College, Bengbu, China.
Jianfeng ZhouDepartment of Pediatric Surgery, Children's Hospital of Nanjing Medical University, Nanjing, China.
Second Affiliated Hospital of Nanjing Medical University · CNFirst Affiliated Hospital of Bengbu Medical College · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Circular RNAs (circRNAs) are non-coding RNAs with covalent closed-loop structures and are widely distributed in eukaryotes, conserved and stable as well as tissue-specific. Malignant solid tumors pose a serious health risk to children and are one of the leading causes of pediatric mortality. Studies have shown that circRNAs play an important regulatory role in the development of childhood malignant solid tumors, hence are potential biomarkers and therapeutic targets for tumors. This paper reviews the biological characteristics and functions of circRNAs as well as the research progress related to childhood malignant solid tumors.

Indexed as

biological functionsbiomarkerscircRNAepigeneticspediatric malignant solid tumors

Identifiers

PMID35116058
PMCPMC8804321
OpenAlexW4206089959

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.