Evidence map›Paper›PMID 35116013›Full record

ArticleFrontiers in microbiology2021

SARS-CoV-2 Vaccination and Protection Against Clinical Disease: A Retrospective Study, Bouches-du-Rhône District, Southern France, 2021.

Pierre-Edouard Fournier, Linda Houhamdi, Philippe Colson, Sébastien Cortaredona, Lea Delorme, Carole Cassagne, Jean-Christophe Lagier, Hervé Chaudet, Hervé Tissot-Dupont, Audrey Giraud-Gatineau and 3 more

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Frontiers in microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07254052 (Effectiveness of a Sustained-release Ammonium Chloride Formulation in Reducing the Viral Load of Patients With COVID-19 or Influenza), which is not on this map. Cited by 5 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 2 pooled it
0.6field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07254052 completednot on this mapstarted 2024, after this paper: background citation

Effectiveness of a Sustained-release Ammonium Chloride Formulation in Reducing the Viral Load of Patients With COVID-19 or Influenza

TypeobservationalSponsorNational and Kapodistrian University of AthensRan2024 to 2025Enrolled32ConditionsRNA Virus Infections, Viral Infection COVID-19, Influenza A and B
3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 2 syntheses or guidelines pooled it, 7 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Observational
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 1 country.

Pierre-Edouard FournierIHU Méditerranée Infection, Marseille, France.
Linda HouhamdiIHU Méditerranée Infection, Marseille, France.
Philippe ColsonIHU Méditerranée Infection, Marseille, France.
Sébastien CortaredonaIHU Méditerranée Infection, Marseille, France.
Lea DelormeIHU Méditerranée Infection, Marseille, France.
Carole CassagneIHU Méditerranée Infection, Marseille, France.
Jean-Christophe LagierIHU Méditerranée Infection, Marseille, France.
Hervé ChaudetIHU Méditerranée Infection, Marseille, France.
Hervé Tissot-DupontIHU Méditerranée Infection, Marseille, France.
Audrey Giraud-GatineauIHU Méditerranée Infection, Marseille, France.
Florence FenollarIHU Méditerranée Infection, Marseille, France.
Matthieu MillionIHU Méditerranée Infection, Marseille, France.
Didier RaoultIHU Méditerranée Infection, Marseille, France.
Méditerranée Infection Foundation · FRCentre de recherche en Epidémiologie et Santé des Populations · FRUnité de Recherche sur les Maladies Infectieuses et Tropicales Emergentes · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

From January 18th to August 13th, 2021, 13,804 unvaccinated and 1,156 patients who had received at least one COVID-19 vaccine dose were tested qPCR-positive for SARS-CoV-2 in our center. Among vaccinated patients, 949, 205 and 2 had received a single, two or three vaccine doses, respectively. Most patients (80.3%) had received the Pfizer-BioNTech vaccine. The SARS-CoV-2 variants infecting vaccinated patients varied over time, reflecting those circulating in the Marseille area, with a predominance of the Marseille-4/20A.EU2 variant from weeks 3 to 6, of the Alpha/20I variant from weeks 7 to 25, and of the Delta/21A variant from week 26. SARS-CoV-2 infection was significantly more likely to occur in the first 13 days post-vaccine injection in those who received a single dose (48.9%) than two doses (27.4%,

Indexed as

COVID-19deathhospitalizationintensive careprotective effectSARS-CoV-2vaccine

Identifiers

PMID35116013
PMCPMC8803903
OpenAlexW4206032888

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.