Evidence map›Paper›PMID 35116012›Full record

ArticleFrontiers in microbiology2021

Jean-Luc C Mougeot, Micaela F Beckman, Holden C Langdon, Rajesh V Lalla, Michael T Brennan, Farah K Bahrani Mougeot

Open access · goldAbstract read
In one paragraph

Article in Frontiers in microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 18 citations in OpenAlex.

  1. Trial
  2. Review
  3. Review
  4. Article
  5. HPV Infection and Oral Microbiota: Interactions and Future Implications.International journal of molecular sciences · 2025
    Review
  6. Article
  7. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Jean-Luc C MougeotCarolinas Medical Center-Atrium Health, Charlotte, NC, United States.
Micaela F BeckmanCarolinas Medical Center-Atrium Health, Charlotte, NC, United States.
Holden C LangdonCarolinas Medical Center-Atrium Health, Charlotte, NC, United States.
Rajesh V LallaSection of Oral Medicine-University of Connecticut Health, Farmington, CT, United States.
Michael T BrennanCarolinas Medical Center-Atrium Health, Charlotte, NC, United States.
Farah K Bahrani MougeotCarolinas Medical Center-Atrium Health, Charlotte, NC, United States.
Carolinas Medical Center · USUConn Health · US

Funding

Long-term Oral Complications of an Established Head and Neck Cancer Cohort- Clinical Registry of Dental Outcomes in Head and Neck Cancer Patients: OraRadU01DE022939 · NIDCR · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI BRENNAN, MICHAEL T, LALLA, RAJESH V. · 2012 to 2023
$16.8M
NIDCR NIH HHS U01 DE022939
6 · The paper itself

Abstract

objectivesHuman papillomavirus (HPV) is a known etiological factor of oropharyngeal head and neck cancer (HNC). HPV positivity and periodontal disease have been associated with higher HNC risk, suggesting a role for oral bacterial species. Our objective was to determine oral microbiome profiles in HNC patients (HPV-positive and HPV-negative) and in healthy controls (HC).

methodsSaliva samples and swabs of buccal mucosa, supragingival plaque, and tongue were collected from HNC patients (

resultsHNC vs. HC and HNC HPV+ vs. HNC HPV- β-diversities differed significantly (pMonte Carlo < 0.05).

conclusionOral microbiome profiles of HNC HPV+ and HNC HPV- patients differed significantly regarding periodontal-associated species. Our results suggest that oral bacterial species (e.g.,

Indexed as

head and neck cancerHPVLeptotrichia spp.next generation sequencingoral microbiome

Identifiers

PMID35116012
PMCPMC8803733
OpenAlexW4205176931

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.