ReviewFrontiers in neurology2021
Olfactory Dysfunction in Patients With Coronavirus Disease 2019: A Review.
Review in Frontiers in neurology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04789499 (Smell in Covid-19 and Efficacy of Nasal Theophylline), which is not on this map. Cited by 13 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Smell in Covid-19 and Efficacy of Nasal Theophylline
Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.
- Pooled it
- Effectiveness of platelet-rich plasma on post-COVID chronic olfactory dysfunction.Revista da Associacao Medica Brasileira (1992) · 2023Trial
- Efficacy and Safety of Saline Nasal Irrigation Plus Theophylline for Treatment of COVID-19-Related Olfactory Dysfunction: The SCENT2 Phase 2 Randomized Clinical Trial.JAMA otolaryngology-- head & neck surgery · 2022Trial
- Review
- Unmasking Risk Factors for Post-COVID-19 Olfactory Dysfunction Resulting From Early Stages of the Pandemic: A Case-Control Study of Lost and Lingering Smells.The Permanente journal · 2025Article
- A Comparative Analysis of the Incidence, Severity and Duration of Smell and Taste Loss in COVID-19 Cases Versus Non-COVID-19 Cases: A Longitudinal Cohort Study.Journal of clinical medicine · 2023Article
- Functions of human olfactory mucus and age-dependent changes.Scientific reports · 2023Article
- Exploring the research landscape of COVID-19-induced olfactory dysfunction: A bibliometric study.Frontiers in neuroscience · 2023Review
- Sociodemographic Characteristics and Comorbidities of Patients With Long COVID and Persistent Olfactory Dysfunction.JAMA network open · 2022Article
- Elevated Expression ofJournal of personalized medicine · 2022Article
- Prevalence and associated factors of depression, anxiety and stress among coronavirus disease 2019 (COVID-19) patients in Herat, Afghanistan.Global health journal (Amsterdam, Netherlands) · 2022Article
- Revealing the mystery of persistent smell loss in Long COVID patients.International journal of biological sciences · 2022Review
- Susceptibility and Severity of COVID-19 Are Both Associated With Lower Overall Viral-Peptide Binding Repertoire of HLA Class I Molecules, Especially in Younger People.Frontiers in immunology · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The coronavirus disease 2019 (COVID-19) pandemic is wreaking havoc on public-health and economic systems worldwide. Among the several neurological symptoms of patients with COVID-19 reported in clinical practice, olfactory dysfunction (OD) is the most common. OD occurs as the earliest or the only clinical manifestation in some patients. Increasing research attention has focused on OD, which is listed as one of the main diagnostic symptoms of severe acute respiratory syndrome-coronavirus-2 infection. Multiple clinical and basic-science studies on COVID-19-induced OD are underway to clarify the underlying mechanism of action. In this review, we summarize the clinical characteristics, mechanisms, evaluation methods, prognosis, and treatment options of COVID-19-induced OD. In this way, we hope to improve the understanding of COVID-19-induced OD to aid early identification and precise intervention.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.