Evidence map›Paper›PMID 35115819›Full record

ArticleInternational journal of general medicine2022

Predicting New-Onset Postoperative Atrial Fibrillation Following Isolated Coronary Artery Bypass Grafting: Development and Validation of a Novel Nomogram.

Kangjun Fan, Liang Chen, Fei Liu, Xiaohang Ding, Pengyun Yan, Mingxin Gao, Wenyuan Yu, Hongli Liu, Yang Yu

Abstract read
In one paragraph

Article in International journal of general medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Kangjun FanDepartment of Cardiac Surgery, Beijing Anzhen Hospital, Capital Medical University, Beijing, 100029, People's Republic of China.
Liang ChenDepartment of Cardiac Surgery, Beijing Anzhen Hospital, Capital Medical University, Beijing, 100029, People's Republic of China.ORCID 0000-0001-8930-9722
Fei LiuDepartment of Biology, Faculty of Science, Hong Kong Baptist College, Kowloon Tong, Hong Kong, People's Republic of China.
Xiaohang DingDepartment of Cardiac Surgery, Beijing Anzhen Hospital, Capital Medical University, Beijing, 100029, People's Republic of China.
Pengyun YanDepartment of Cardiac Surgery, Beijing Anzhen Hospital, Capital Medical University, Beijing, 100029, People's Republic of China.ORCID 0000-0002-0653-5044
Mingxin GaoDepartment of Cardiac Surgery, Beijing Anzhen Hospital, Capital Medical University, Beijing, 100029, People's Republic of China.
Wenyuan YuDepartment of Cardiac Surgery, Beijing Anzhen Hospital, Capital Medical University, Beijing, 100029, People's Republic of China.
Hongli LiuDepartment of Cardiac Surgery, Beijing Anzhen Hospital, Capital Medical University, Beijing, 100029, People's Republic of China.
Yang YuDepartment of Cardiac Surgery, Beijing Anzhen Hospital, Capital Medical University, Beijing, 100029, People's Republic of China.ORCID 0000-0002-8482-4626

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo select variables associated with new-onset postoperative atrial fibrillation (POAF) following isolated coronary artery bypass grafting (CABG) and develop a nomogram for risk prediction in a Chinese population.

methodsThe study retrospectively enrolled 4854 consecutive patients undergoing isolated CABG from February 2018 to September 2019, they were divided into derivation cohort and validation cohort with a 3:1 ratio according to the order of operation date. In the derivation cohort, significant variables were selected by use of the multivariate logistic backward stepwise regression analysis and a nomogram model was built on the strength of the results. The model performance was assessed in terms of discrimination and calibration. Besides, we compared the discriminative ability for POAF of the nomogram with established prediction models (CHA2DS2-VASc and HATCH scores) in the two cohorts.

resultsPOAF occurred in 1025 (28.2%) out of 3641 patients in the derivation cohort, and in 337 (27.8%) out of 1213 patients in the validation cohort. A nomogram, composed of eight prognostic variables, namely age, sex, heart rate, hypertension, left ventricular ejection fraction (LVEF) <50%, left atrial diameter (LAD) > 40mm, estimated glomerular filtration rate (eGFR) level, and on-pump surgery, was constructed from the derivation cohort. The nomogram had substantial discriminative ability in derivation and validation cohorts with the area under the receiver operating characteristic curves (AUCs) of 0.661 (95% confidence interval, 0.642-0.681) and 0.665 (95% confidence interval, 0.631-0.699), respectively, and showed well-fitted calibration curves. Compared with CHA2DS2-VASc, HATCH and POAF scores, respectively, the nomogram had superior discrimination performance.

conclusionWe constructed a novel nomogram with improved accuracy for predicting the risk of POAF following isolated CABG, which might help clinicians predict individual probability of POAF and achieve effective prophylaxis.

Indexed as

atrial fibrillationcoronary artery bypass graftinghigh-risk patientsnomogramprediction

Identifiers

PMID35115819
PMCPMC8801512

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.