Evidence map›Paper›PMID 35115681›Full record

ArticleInternational journal of impotence research2023

U-shaped association between prevalence of secondary hypogonadism and body mass index: a retrospective analysis of men with testosterone deficiency.

Aaron A Gurayah, Matthew M Mason, John M Masterson, Atil Y Kargi, Ranjith Ramasamy

Open access · greenAbstract read
In one paragraph

Article in International journal of impotence research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. The Impact of Visceral Adiposity on Testosterone Levels in American Adult Men: A Cross-Sectional Analysis.Medical science monitor : international medical journal of experimental and clinical research · 2023
    Article
  5. Review
  6. Review
  7. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Aaron A GurayahUniversity of Miami Miller School of Medicine, Miami, FL, USA.ORCID http://orcid.org/0000-0002-5876-9651
Matthew M MasonUniversity of Miami Miller School of Medicine, Miami, FL, USA.ORCID http://orcid.org/0000-0002-0427-459X
John M MastersonDepartment of Urology, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
Atil Y KargiDepartment of Endocrinology, University of Miami Miller School of Medicine, Miami, FL, USA.
Ranjith RamasamyDepartment of Urology, University of Miami Miller School of Medicine, Miami, FL, USA. ramasamy@miami.edu.ORCID http://orcid.org/0000-0003-1387-7904
University of Miami · USCedars-Sinai Medical Center · US

Funding

Disease Modifying Treatment Using Combined Shockwave Therapy and Platelet Rich Plasma In Microvascular Erectile DysfunctionR01DK130991 · NIDDK · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI IBRAHIM, EMAD · 2021 to 2023
$921k
NIDDK NIH HHS R01 DK130991
6 · The paper itself

Abstract

The prevalence of both obesity and hypogonadism in the United States has increased over the past two decades. While prior studies have shown an association between obesity and secondary hypogonadism-low testosterone and luteinizing hormone-few have used a large enough sample size to determine prevalence at each body mass index class. We aimed to compare rates of secondary hypogonadism among body mass index classes by constructing a retrospective database with men who had their body mass index, morning testosterone and luteinizing hormone levels measured during a visit to a urology clinic at a tertiary academic medical center between 2011-2020. Men previously on testosterone replacement therapy, Clomiphene, or Anastrozole were excluded. Chi-squared analysis was conducted in "R". We found that among the 7211 men studied, 45.7%, 22.6%, and 4.4% were classified as having diagnosis of secondary, primary, and compensated hypogonadism, respectively. We found that obese men and underweight men had increased prevalence of secondary hypogonadism as compared to men with normal body mass index. These findings support the need for routine screening criteria and personalized advice to patients dealing with secondary hypogonadism.

Indexed as

HypogonadismBody Mass IndexHumansLuteinizing HormoneMaleObesityPrevalenceRetrospective StudiesTestosteroneLuteinizing HormoneTestosterone

Identifiers

PMID35115681
PMCPMC9346090
OpenAlexW4210620717

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.