ArticleScientific reports2022
Accuracy of core needle biopsy for histologic diagnosis of soft tissue sarcoma.
Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed, 35 citations in OpenAlex.
- Multi-b-value diffusion-weighted imaging-based habitat imaging for preoperative prediction of histological grade and prognosis in soft tissue sarcoma: focusing on intratumoral heterogeneity.Quantitative imaging in medicine and surgery · 2026Article
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- Diagnosis and Management of Soft-Tissue Sarcomas: Current Insights.Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews · 2026Review
- Clinical and radiological features of primary breast sarcoma: a 14-year retrospective case series from a single institution.International journal of surgery case reports · 2026Article
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- A case of pelvic Ewing sarcoma misinterpreted as osteomyelitis: diagnostic and clinical implications.Radiology case reports · 2026Article
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- ASO Practice Guidelines Series: Soft Tissue Sarcoma of the Extremities and Superficial Trunk.Annals of surgical oncology · 2025Review
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- Case report: Primary cardiac synovial sarcoma with suspected connective tissue disease diagnosed by EBUS-TBMB.Frontiers in medicine · 2025Article
- Research on application of multiparametric MRI to predict FNCLCC grading and ki67 expression in soft tissue sarcoma biopsy pathology: Based on a CT-MRI fusion image registration method.Frontiers in oncology · 2025Article
- Ultrasound guided procedures in the musculoskeletal system: a narrative review with illustrative examples.Quantitative imaging in medicine and surgery · 2024Review
- Diagnosis and Management of Desmoid Fibromatosis of the Breast.World journal of oncology · 2024Review
- Case report: Para-testicular spindle cell lipoma suspected of well-differentiated liposarcoma.Frontiers in urology · 2024Article
- Lymphadenectomy in the treatment of sarcomas - indications and technique.Oncology reviews · 2024Review
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The biopsy technique of choice in soft tissue sarcoma (STS) diagnosis is controversial. We examined the diagnostic accuracy of percutaneous core needle biopsy (CNB) and compared it to open incisional biopsy. A retrospective study included 91 incisional biopsies and 102 CNBs. A pair-match investigation was conducted on 19 patient pairs, comparing sensitivity, specificity, and diagnostic accuracy. Furthermore, we investigated the role of molecular pathology in sarcoma diagnostics. In 81/91 (89%) patients with incisional biopsy, the entity was confirmed by definitive pathology, whereas this was the case in 89/102 (87%) CNB patients (p = 0.52). Grading remained unchanged in 46/55 (84%) of incisional and 54/62 (87%) of CNBs (p = 0.61). The pair matched analysis showed that the correct entity was determined in 96% of incisional and 97.6% of core needle biopsies. The time between the initial consultation and the interdisciplinary tumor board's treatment recommendation was shorter in core needle biopsies (8.37 vs. 15.63 days; p < 0.002). Incisional biopsies led to two wound infections and one hematoma, whereas wound infection occurred in one patient after CNB. CNB leads to faster diagnosis while reaching the same histological accuracy and is less burdensome for patients. Still, surgeons need to remain aware of the possibility of biopsy failure.
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