ArticleNature communications2022
Multiple expansions of globally uncommon SARS-CoV-2 lineages in Nigeria.
Article in Nature communications, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
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Who cites it
33 citing papers in PubMed.
- SARS-CoV-2 Omicron infection reveals imprinted antibody responses in the absence of vaccination.iScience · 2026Article
- Article
- Two years of SARS-CoV-2 genomic surveillance capacity development in Guinea.Scientific reports · 2026Article
- Genomic surveillance and phylo-evolutionary analysis of SARS-CoV-2 variants in Osun state, Nigeria during the second wave of COVID-19 pandemic.BMC medical genomics · 2025Article
- Phylodynamics of SARS-CoV-2 Lineages B.1.1.7, B.1.1.529 and B.1.617.2 in Nigeria Suggests Divergent Evolutionary Trajectories.Pathogens (Basel, Switzerland) · 2025Article
- Genomic diversity and surveillance of SARS-CoV-2 in Nigeria.BMC genomics · 2025Article
- Circulation of SARS-CoV-2 and Co-Infection withInfectious disease reports · 2025Article
- Genomic Surveillance of SARS-CoV-2 in Ibadan, Oyo State, Nigeria.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2025Article
- Review
- Genomic and epidemiological analysis of SARS-CoV-2 variants isolated in Guinea: a routine sequencing implementation.BMC infectious diseases · 2025Article
- Routes of importation and spatial dynamics of SARS-CoV-2 variants during localized interventions in Chile.PNAS nexus · 2024Article
- Review
- An updated framework for SARS-CoV-2 variants reflects the unpredictability of viral evolution.Nature medicine · 2024Article
- Whole genome sequencing and phylogenetic analysis of SARS-CoV-2 strains isolated during the COVID-19 pandemic in Nigeria.IJID regions · 2024Article
- First Molecular Detection of SARS-CoV-2 in Sewage and Wastewater in Ghana.BioMed research international · 2024Article
- Article
- Review
- Resurgence of SARS-CoV-2 Delta after Omicron variant superinfection in an immunocompromised pediatric patient.Virology journal · 2023Article
- COVID-19 in 16 West African Countries: An Assessment of the Epidemiology and Genetic Diversity of SARS-CoV-2 after Four Epidemic Waves.The American journal of tropical medicine and hygiene · 2023Review
- Review
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20 authors.
Funding
Abstract
Disparities in SARS-CoV-2 genomic surveillance have limited our understanding of the viral population dynamics and may delay identification of globally important variants. Despite being the most populated country in Africa, Nigeria has remained critically under sampled. Here, we report sequences from 378 SARS-CoV-2 isolates collected in Oyo State, Nigeria between July 2020 and August 2021. In early 2021, most isolates belonged to the Alpha "variant of concern" (VOC) or the Eta lineage. Eta outcompeted Alpha in Nigeria and across West Africa, persisting in the region even after expansion of an otherwise rare Delta sub-lineage. Spike protein from the Eta variant conferred increased infectivity and decreased neutralization by convalescent sera in vitro. Phylodynamic reconstructions suggest that Eta originated in West Africa before spreading globally and represented a VOC in early 2021. These results demonstrate a distinct distribution of SARS-CoV-2 lineages in Nigeria, and emphasize the need for improved genomic surveillance worldwide.
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