Evidence map›Paper›PMID 35115383›Full record

ArticleeNeuro

Heterozygous

Louise Thiry, Chloé Lemaire, Ali Rastqar, Maxime Lemieux, Jimmy Peng, Julien Ferent, Marie Roussel, Eric Beaumont, James P Fawcett, Robert M Brownstone and 2 more

Abstract read
In one paragraph

Article in eNeuro. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Corticospinal Tract Development, Evolution, and Skilled Movements.Movement disorders : official journal of the Movement Disorder Society · 2025
    Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Louise ThiryCentre de Recherche du Centre Hospitalier Universitaire (CHU) de Québec-Université Laval, Centre Hospitalier de l'Université Laval (CHUL)-Neurosciences P09800, Quebec City, Quebec G1V 4G2, Canada.
Chloé LemaireCentre de Recherche du Centre Hospitalier Universitaire (CHU) de Québec-Université Laval, Centre Hospitalier de l'Université Laval (CHUL)-Neurosciences P09800, Quebec City, Quebec G1V 4G2, Canada.
Ali RastqarCentre de Recherche du Centre Hospitalier Universitaire (CHU) de Québec-Université Laval, Centre Hospitalier de l'Université Laval (CHUL)-Neurosciences P09800, Quebec City, Quebec G1V 4G2, Canada.
Maxime LemieuxCentre de Recherche du Centre Hospitalier Universitaire (CHU) de Québec-Université Laval, Centre Hospitalier de l'Université Laval (CHUL)-Neurosciences P09800, Quebec City, Quebec G1V 4G2, Canada.
Jimmy PengInstitut de Recherches Cliniques de Montréal (IRCM), Montréal, Quebec H2W 1R7, Canada.
Julien FerentInstitut de Recherches Cliniques de Montréal (IRCM), Montréal, Quebec H2W 1R7, Canada.
Marie RousselCentre de Recherche du Centre Hospitalier Universitaire (CHU) de Québec-Université Laval, Centre Hospitalier de l'Université Laval (CHUL)-Neurosciences P09800, Quebec City, Quebec G1V 4G2, Canada.
Eric BeaumontDepartment of Biomedical Sciences, Quillen College of Medicine, East Tennessee State University, Johnson City, TN 37604.
James P FawcettDepartment of Pharmacology, Dalhousie University, Halifax, Nova Scotia B3H 4R2, Canada.
Robert M BrownstoneUniversity College London (UCL) Queen Square Institute of Neurology, University College London, London WC1N 3BG, United Kingdom.ORCID 0000-0001-5135-2725
Frédéric CharronInstitut de Recherches Cliniques de Montréal (IRCM), Montréal, Quebec H2W 1R7, Canada frederic.charron@ircm.qc.ca frederic.bretzner.1@ulaval.ca.ORCID 0000-0003-3483-8672
Frédéric BretznerCentre de Recherche du Centre Hospitalier Universitaire (CHU) de Québec-Université Laval, Centre Hospitalier de l'Université Laval (CHUL)-Neurosciences P09800, Quebec City, Quebec G1V 4G2, Canada frederic.charron@ircm.qc.ca frederic.bretzner.1@ulaval.ca.ORCID 0000-0002-7387-3414

Funding

CIHR 334023
6 · The paper itself

Abstract

Axon guidance receptors such as deleted in colorectal cancer (DCC) contribute to the normal formation of neural circuits, and their mutations can be associated with neural defects. In humans, heterozygous mutations in

Indexed as

LocomotionPyramidal TractsAnimalsDCC ReceptorHeterozygoteMiceMotor NeuronsPhenotypeDcc protein, mouseDCC ReceptorCPGDcclocomotionmutant mice

Identifiers

PMID35115383
PMCPMC8906791

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.