Evidence map›Paper›PMID 35115382›Full record

ArticleeNeuro

Chronic hM4Di-DREADD-Mediated Chemogenetic Inhibition of Forebrain Excitatory Neurons in Postnatal or Juvenile Life Does Not Alter Adult Mood-Related Behavior.

Praachi Tiwari, Darshana Kapri, Amartya Pradhan, Angarika Balakrishnan, Pratik R Chaudhari, Vidita A Vaidya

Open access · goldAbstract read
In one paragraph

Article in eNeuro. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.8field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Chemogenetic modulation of CNS pericytes: Impact on pericyte CaMolecular therapy : the journal of the American Society of Gene Therapy · 2026
    Article
  3. Article
  4. Article
  5. The lateral habenula is required for maternal behavior in the mouse dam.bioRxiv : the preprint server for biology · 2024
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Praachi TiwariDepartment of Biological Sciences, Tata Institute of Fundamental Research, Mumbai 400005, India.
Darshana KapriDepartment of Biological Sciences, Tata Institute of Fundamental Research, Mumbai 400005, India.
Amartya PradhanDepartment of Biological Sciences, Tata Institute of Fundamental Research, Mumbai 400005, India.ORCID 0000-0001-7575-8404
Angarika BalakrishnanDepartment of Biological Sciences, Tata Institute of Fundamental Research, Mumbai 400005, India.
Pratik R ChaudhariDepartment of Biological Sciences, Tata Institute of Fundamental Research, Mumbai 400005, India.
Vidita A VaidyaDepartment of Biological Sciences, Tata Institute of Fundamental Research, Mumbai 400005, India vvaidya@tifr.res.in.ORCID 0000-0002-3907-8580
Tata Institute of Fundamental Research · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

G-protein-coupled receptors (GPCRs) coupled to G

Indexed as

ClozapineNeuronsAffectAnimalsHippocampusMiceProsencephalonSynaptic TransmissionClozapineanxietydepressionDREADDearly lifeGi signalingschizophrenia

Identifiers

PMID35115382
PMCPMC8856708
OpenAlexW4225463274

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.