Evidence map›Paper›PMID 35115379›Full record

ArticleGenes & development2022

Parental histone deposition on the replicated strands promotes error-free DNA damage tolerance and regulates drug resistance.

Valeria Dolce, Sabrina Dusi, Michele Giannattasio, Chinnu Rose Joseph, Marco Fumasoni, Dana Branzei

Open access · diamondAbstract read
In one paragraph

Article in Genes & development, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 19 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Valeria DolceIstituto FIRC (Fondazione Italiana per la Ricerca sul Cancro) di Oncologia Molecolare (IFOM), the FIRC Institute of Molecular Oncology, 20139 Milan, Italy.
Sabrina DusiIstituto FIRC (Fondazione Italiana per la Ricerca sul Cancro) di Oncologia Molecolare (IFOM), the FIRC Institute of Molecular Oncology, 20139 Milan, Italy.
Michele GiannattasioIstituto FIRC (Fondazione Italiana per la Ricerca sul Cancro) di Oncologia Molecolare (IFOM), the FIRC Institute of Molecular Oncology, 20139 Milan, Italy.
Chinnu Rose JosephIstituto FIRC (Fondazione Italiana per la Ricerca sul Cancro) di Oncologia Molecolare (IFOM), the FIRC Institute of Molecular Oncology, 20139 Milan, Italy.
Marco FumasoniIstituto FIRC (Fondazione Italiana per la Ricerca sul Cancro) di Oncologia Molecolare (IFOM), the FIRC Institute of Molecular Oncology, 20139 Milan, Italy.
Dana BranzeiIstituto FIRC (Fondazione Italiana per la Ricerca sul Cancro) di Oncologia Molecolare (IFOM), the FIRC Institute of Molecular Oncology, 20139 Milan, Italy.
FIRC Institute of Molecular Oncology · ITIstituto di Genetica Molecolare · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ctf4 is a conserved replisome component with multiple roles in DNA metabolism. To investigate connections between Ctf4-mediated processes involved in drug resistance, we conducted a suppressor screen of

Indexed as

HistonesSaccharomyces cerevisiae ProteinsDNA-Binding ProteinsDNA DamageDNA ReplicationDrug ResistanceSaccharomyces cerevisiaeCTF4 protein, S cerevisiaeDNA-Binding ProteinsHistonesSaccharomyces cerevisiae ProteinsDNA damage toleranceDpb3–Dpb4histone depositionMcm2–Ctf4–Polαmutagenesisrecombinationreplication fork

Identifiers

PMID35115379
PMCPMC8887126
OpenAlexW4210248006

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.