Evidence map›Paper›PMID 35115376›Full record

ArticleCMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne2022

Nirmatrelvir-ritonavir for COVID-19.

Emily G McDonald, Todd C Lee

Abstract readComment
In one paragraph

Article in CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Low-Data Drug Design with Few-Shot Generative Domain Adaptation.Bioengineering (Basel, Switzerland) · 2023
    Article
  5. Article
  6. Review
  7. Review
  8. Review
  9. Renalism.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2022
    Article
  10. Benefits of nirmatrelvir-ritonavir remain unproven for some populations.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2022
    Article
  11. Article
  12. Review
  13. Real-world effectiveness ofFrontiers in pharmacology · 2022
    Article
  14. Paxlovid: Mechanism of Action, Synthesis, andBioMed research international · 2022
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Emily G McDonaldClinical Practice Assessment Unit (McDonald, Lee), and Divisions of Internal Medicine (McDonald) and Infectious Diseases (Lee), Department of Medicine, McGill University Health Centre, Montréal, Que. emily.mcdonald@mcgill.ca.
Todd C LeeClinical Practice Assessment Unit (McDonald, Lee), and Divisions of Internal Medicine (McDonald) and Infectious Diseases (Lee), Department of Medicine, McGill University Health Centre, Montréal, Que.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

COVID-19 Drug TreatmentAdministration, OralCytochrome P-450 CYP3A InhibitorsDrug CombinationsDrug InteractionsHumansLactamsLeucineNitrilesProlineRitonavirSARS-CoV-2Viral Protease InhibitorsCytochrome P-450 CYP3A InhibitorsDrug CombinationsLactamsLeucinenirmatrelvirNitrilesProlineRitonavirViral Protease Inhibitors

Identifiers

PMID35115376
PMCPMC8900806

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.