Evidence map›Paper›PMID 35115105›Full record

ReviewJournal of the American College of Cardiology2022

Interventions for Frailty Among Older Adults With Cardiovascular Disease: JACC State-of-the-Art Review.

Naila Ijaz, Brian Buta, Qian-Li Xue, Denise T Mohess, Archana Bushan, Henry Tran, Wayne Batchelor, Christopher R deFilippi, Jeremy D Walston, Karen Bandeen-Roche and 5 more

Open access · hybridAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Journal of the American College of Cardiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 236 papers, 8 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
236citing papers in PubMed, 8 pooled it
43.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

236 citing papers in PubMed, 8 syntheses or guidelines pooled it, 366 citations in OpenAlex.

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176 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 4 institutions in 1 country.

Naila IjazThe Inova Center of Outcomes Research, Inova Heart and Vascular Institute, Falls Church, Virginia, USA.
Brian ButaJohns Hopkins Older Americans Independence Center and the Center on Aging and Health, Johns Hopkins University, Baltimore, Maryland, USA.
Qian-Li XueDivision of Geriatrics and Gerontology, Department of Medicine, Johns Hopkins School of Medicine, Baltimore, Maryland, USA.
Denise T MohessThe Inova Center of Outcomes Research, Inova Heart and Vascular Institute, Falls Church, Virginia, USA; Division of Geriatric Medicine, Department of Medicine, Inova Heath, Falls Church, Virginia, USA.
Archana BushanThe Inova Center of Outcomes Research, Inova Heart and Vascular Institute, Falls Church, Virginia, USA; Division of Geriatric Medicine, Department of Medicine, Inova Heath, Falls Church, Virginia, USA.
Henry TranThe Inova Center of Outcomes Research, Inova Heart and Vascular Institute, Falls Church, Virginia, USA.
Wayne BatchelorThe Inova Center of Outcomes Research, Inova Heart and Vascular Institute, Falls Church, Virginia, USA.
Christopher R deFilippiThe Inova Center of Outcomes Research, Inova Heart and Vascular Institute, Falls Church, Virginia, USA.
Jeremy D WalstonJohns Hopkins Older Americans Independence Center and the Center on Aging and Health, Johns Hopkins University, Baltimore, Maryland, USA; Division of Geriatrics and Gerontology, Department of Medicine, Johns Hopkins School of Medicine, Baltimore, Maryland, USA.
Karen Bandeen-RocheJohns Hopkins Older Americans Independence Center and the Center on Aging and Health, Johns Hopkins University, Baltimore, Maryland, USA.
Daniel E FormanGeriatric Cardiology Section, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
Jon R ResarDivision of Cardiology, Department of Medicine, Johns Hopkins School of Medicine, Baltimore, Maryland, USA.
Christopher M O'ConnorThe Inova Center of Outcomes Research, Inova Heart and Vascular Institute, Falls Church, Virginia, USA.
Gary GerstenblithJohns Hopkins Older Americans Independence Center and the Center on Aging and Health, Johns Hopkins University, Baltimore, Maryland, USA; Division of Cardiology, Department of Medicine, Johns Hopkins School of Medicine, Baltimore, Maryland, USA.
Abdulla A DamlujiThe Inova Center of Outcomes Research, Inova Heart and Vascular Institute, Falls Church, Virginia, USA; Johns Hopkins Older Americans Independence Center and the Center on Aging and Health, Johns Hopkins University, Baltimore, Maryland, USA; Division of Cardiology, Department of Medicine, Johns Hopkins School of Medicine, Baltimore, Maryland, USA. Electronic address: abdulla.damluji@jhu.edu.
Inova Health System · USJohns Hopkins University · USJohns Hopkins Medicine · USUniversity of Pittsburgh · US

Funding

Technological Assessment and Solutions Core - RC4P30AG021334 · NIA · JOHNS HOPKINS UNIVERSITY · PI Jeremy D Walston · 2003 to 2026
$33.2M
Frailty and Resiliency in Older Adults with Acute Myocardial InfarctionK23HL153771 · NHLBI · INOVA HEALTH CARE SERVICES · PI DAMLUJI, ABDULLA AL · 2020 to 2024
$916k
NHLBI NIH HHS K23 HL153771NIA NIH HHS P30 AG021334
6 · The paper itself

Abstract

With the aging of the world's population, a large proportion of patients seen in cardiovascular practice are older adults, but many patients also exhibit signs of physical frailty. Cardiovascular disease and frailty are interdependent and have the same physiological underpinning that predisposes to the progression of both disease processes. Frailty can be defined as a phenomenon of increased vulnerability to stressors due to decreased physiological reserves in older patients and thus leads to poor clinical outcomes after cardiovascular insults. There are various pathophysiologic mechanisms for the development of frailty: cognitive decline, physical inactivity, poor nutrition, and lack of social supports; these risk factors provide opportunity for various types of interventions that aim to prevent, improve, or reverse the development of frailty syndrome in the context of cardiovascular disease. There is no compelling study demonstrating a successful intervention to improve a global measure of frailty. Emerging data from patients admitted with heart failure indicate that interventions associated with positive outcomes on frailty and physical function are multidimensional and include tailored cardiac rehabilitation. Contemporary cardiovascular practice should actively identify patients with physical frailty who could benefit from frailty interventions and aim to deliver these therapies in a patient-centered model to optimize quality of life, particularly after cardiovascular interventions.

Indexed as

Quality of LifeAgedAgingCardiac RehabilitationCardiovascular DiseasesFrail ElderlyFrailtyHumansRisk Factorsagingcardiovascular diseasefrailtyinterventionsolder adult

Identifiers

PMID35115105
PMCPMC8852369
OpenAlexW4210642841

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.