Evidence map›Paper›PMID 35114849›Full record

ArticleJournal of dental research2022

Wnt/β-catenin Signaling Controls Maxillofacial Hyperostosis.

J Chen, P L Cuevas, J S Dworan, I Dawid, H Turkkahraman, K Tran, J Delgado-Calle, T Bellido, J P Gorski, B Liu and 2 more

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of dental research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 6 institutions in 3 countries.

J ChenDivision of Plastic and Reconstructive Surgery, Department of Surgery, Stanford University School of Medicine, Palo Alto, CA, USA.
P L CuevasDivision of Plastic and Reconstructive Surgery, Department of Surgery, Stanford University School of Medicine, Palo Alto, CA, USA.
J S DworanDivision of Plastic and Reconstructive Surgery, Department of Surgery, Stanford University School of Medicine, Palo Alto, CA, USA.
I DawidDivision of Plastic and Reconstructive Surgery, Department of Surgery, Stanford University School of Medicine, Palo Alto, CA, USA.
H TurkkahramanIndiana University School of Dentistry, Department of Orthodontics & Oral Facial Genetics, Indianapolis, IN, USA.ORCID 0000-0001-9052-7700
K TranDivision of Plastic and Reconstructive Surgery, Department of Surgery, Stanford University School of Medicine, Palo Alto, CA, USA.
J Delgado-CalleDepartment of Physiology & Biophysics, University of Arkansas for Medical Sciences, Little Rock, AR, USA.
T BellidoDepartment of Physiology & Biophysics, University of Arkansas for Medical Sciences, Little Rock, AR, USA.
J P GorskiDepartment of Oral and Craniofacial Sciences, School of Dentistry, and Center of Excellence in Mineralized Tissue Research, University of Missouri-Kansas City, Kansas City, MO, USA.ORCID 0000-0002-4452-6704
B LiuDivision of Plastic and Reconstructive Surgery, Department of Surgery, Stanford University School of Medicine, Palo Alto, CA, USA.
J B BrunskiDivision of Plastic and Reconstructive Surgery, Department of Surgery, Stanford University School of Medicine, Palo Alto, CA, USA.
J A HelmsDivision of Plastic and Reconstructive Surgery, Department of Surgery, Stanford University School of Medicine, Palo Alto, CA, USA.ORCID 0000-0002-0463-396X
Stanford University · USUniversity of Arkansas for Medical Sciences · USIndiana University – Purdue University Indianapolis · USMedical University of Vienna · ATSichuan University · CNUniversity of Missouri–Kansas City · US

Funding

Contribution of Osteocytes to the Musculoskeletal Effects of Multiple MyelomaR01CA209882 · NCI · UNIV OF ARKANSAS FOR MED SCIS · PI Teresita M. Bellido, Jesus Delgado-Calle · 2017 to 2026
$3.8M
Glucocorticoid-induced Atrophy in Bone and MuscleR01AR059357 · NIAMS · UNIV OF ARKANSAS FOR MED SCIS · PI BELLIDO, TERESITA M. · 2011 to 2022
$3.4M
BLRD VA I01 BX002104BLRD VA IK6 BX004596NCI NIH HHS R01 CA209882NIAMS NIH HHS R01 AR059357
6 · The paper itself

Abstract

The roles of Wnt/β-catenin signaling in regulating the morphology and microstructure of craniomaxillofacial (CMF) bones was explored using mice carrying a constitutively active form of β-catenin in activating Dmp1-expressing cells (e.g., daβcat

Indexed as

beta CateninHyperostosisAnimalsMiceOsteoblastsOsteocytesWnt Signaling Pathwaybeta Catenincongenital cortical hyperostosiscraniofacial abnormalitiescraniotubular disordersfacial bonesperiosteumWnt signaling pathway

Identifiers

PMID35114849
PMCPMC10850863
OpenAlexW4210699469

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.